Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension

Although pulmonary thromboendarterectomy is increasingly successful for the definitive treatment of chronic thromboembolic pulmonary hypertension (CTEPH), not all patients have surgically accessible disease. Others are poor surgical candidates because of comorbid illness. Therefore, for selected pat...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2001-01, Vol.103 (1), p.10-13
Main Authors: FEINSTEIN, Jeffrey A, GOLDHABER, Samuel Z, LOCK, James E, FERNDANDES, Susan M, LANDZBERG, Michael J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Angioplasty, Balloon - adverse effects
Angioplasty, Balloon - mortality
Biological and medical sciences
Chronic Disease
Diseases of the cardiovascular system
Diuretics - therapeutic use
Follow-Up Studies
Hemodynamics
Humans
Hypertension, Pulmonary - etiology
Hypertension, Pulmonary - surgery
Medical sciences
Middle Aged
Oxygen Inhalation Therapy
Pulmonary Edema - etiology
Pulmonary Edema - therapy
Pulmonary Embolism - complications
Pulmonary Embolism - surgery
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Treatment Outcome
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Summary:Although pulmonary thromboendarterectomy is increasingly successful for the definitive treatment of chronic thromboembolic pulmonary hypertension (CTEPH), not all patients have surgically accessible disease. Others are poor surgical candidates because of comorbid illness. Therefore, for selected patients, we defined and implemented an alternative interventional strategy of balloon pulmonary angioplasty (BPA). Eighteen patients (mean age, 51.8 years; range, 14 to 75 years) with CTEPH underwent BPA; they averaged 2.6 procedures (range, 1 to 5) and 6 dilations (range, 1 to 12). Selection of pulmonary artery segments for dilation required (1) complete occlusion, (2) filling defects, or (3) signs of intravascular webs. After an average of 36 months of follow-up (range, 0.5 to 66 months), the average New York Heart Association class improved from 3.3 to 1.8 (P:
ISSN:0009-7322
1524-4539
DOI:10.1161/01.cir.103.1.10