Ingested acidic food and liquids may lead to misinterpretation of 24-hour ambulatory pH tests : Focus on measurement of extra-esophageal reflux

Normal values of extra-esophageal reflux are difficult to determine owing to variation in the location of the proximal electrode, limited information on the ingestion of acidic food, different exclusion periods for meals, and poor reproducibility of measurement of extra-esophageal reflux. We studied...

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Bibliographic Details
Published in:Digestive diseases and sciences 2007-07, Vol.52 (7), p.1678-1684
Main Authors: KOSKENVUO, Juha W, PÄRKKÄ, Jussi P, HARTIALA, Jaakko J, KINNUNEN, Ilpo, PELTOLA, Matti, SALA, Eeva
Format: Article
Language:English
Subjects:
Adult
Beverages
Biological and medical sciences
Catheters
Dietary restrictions
Electrodes
Esophageal pH Monitoring - standards
Esophagus
False Positive Reactions
Female
Food
Gastroenterology. Liver. Pancreas. Abdomen
Gastroesophageal reflux
Gastroesophageal Reflux - diagnosis
Humans
Hydrogen-Ion Concentration
Male
Meals
Medical diagnosis
Medical sciences
Other diseases. Semiology
Otolaryngology
Otorhinolaryngology. Stomatology
Reproducibility
Time Factors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Summary:Normal values of extra-esophageal reflux are difficult to determine owing to variation in the location of the proximal electrode, limited information on the ingestion of acidic food, different exclusion periods for meals, and poor reproducibility of measurement of extra-esophageal reflux. We studied whether ambulatory esophageal pH testing is disturbed by acidic food ingestion. Eighteen healthy subjects were enrolled in standard dual-channel esophageal pH tests (recorder 1). Ten subjects were equipped with another pH device (recorder 2), positioned to measure extra-esophageal reflux. The subjects were exposed to controlled ingestion of different acidic food or liquid for five 1-min periods. The present study showed that acidic food ingestion for 5 min has a significant effect on the outcome of standard dual-channel ambulatory pH testing. Reflux occurs equally on proximal channels during ingestion of acidic food, whether the proximal channel position is normal or 2 cm above the upper esophageal sphincter. We recommend avoiding acidic food intake during esophageal pH testing.
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-006-9690-3