Influence of HIV Infection on Presentation of Kaposi's Sarcoma

We report a retrospective review of 57 patients with endemic Kaposi's sarcoma (EKS) seen between 1981 and 1990 and 40 prospectively diagnosed patients with and without human immunodeficiency virus (HIV) infection seen between 1991 and 1995. In the retrospective study 52 patients were males and...

Full description

Saved in:
Bibliographic Details
Published in:Tropical doctor 2001-01, Vol.31 (1), p.42-45
Main Authors: Ahmed, Adamu, Isa, Mohamed S, Garba, Habib A, Kalayi, G D, Muhammad, I, Egler, L J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Aged
Biological and medical sciences
Child
Child, Preschool
Female
HIV Infections - complications
Human viral diseases
Humans
Infant
Infectious diseases
Male
Medical sciences
Middle Aged
Nigeria - epidemiology
Prospective Studies
Retrospective Studies
Sarcoma, Kaposi - diagnosis
Sarcoma, Kaposi - epidemiology
Sarcoma, Kaposi - virology
Skin Neoplasms - diagnosis
Skin Neoplasms - epidemiology
Skin Neoplasms - virology
Tropical medicine
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report a retrospective review of 57 patients with endemic Kaposi's sarcoma (EKS) seen between 1981 and 1990 and 40 prospectively diagnosed patients with and without human immunodeficiency virus (HIV) infection seen between 1991 and 1995. In the retrospective study 52 patients were males and five were females. Their ages ranged between 15 and 62 years with a mean of 39 years. Thirty-five (61%) patients had symptoms for more than 1 year. Nodular KS was seen in 75% of the patients. In the prospective study 26 patients had EKS while 14 had AIDS associated KS (AAKS). Among the patients with EKS 24 were males and two were females. The mean duration of symptoms was 20 months. The CD4 count done on nine patients ranged between 900 and 1300 cells/mm3 and there was no mortality within 1 year of presentation. Eleven of the patients with AAKS were males and three were females. Their ages ranged between 22 months and 41 years with a mean of 26. Nine patients had symptoms for less than 6 months. Ten patients had peripheral lymphadenopathy. CD4 counts done on 11 patients ranged between 200 and 800 cells/mm3. Five patients (35%) died within 6 months of presentation. Between 1991 and 1995, 486 patients were seen with HIV infection. Patients with AAKS present with fulminant disease which seemed quickly fatal.
ISSN:0049-4755
1758-1133
DOI:10.1177/004947550103100119