Enantioseparations in counter-current chromatography and centrifugal partition chromatography

Examples of chiral separations in counter-current chromatography (CCC) and centrifugal partition chromatography (CPC) are not numerous, due to the difficulty of finding chiral selectors highly selective in the liquid phase as well as a combination of solvents that does not destroy the selectivity an...

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Bibliographic Details
Published in:Journal of Chromatography A 2001-01, Vol.906 (1), p.365-378
Main Author: Foucault, A.P
Format: Article
Language:English
Subjects:
Albumin
Chromatography, Liquid - methods
Cyclodextrins
N-Dodecanoyl- l-proline-3,5-dimethylanilide
Stereoisomerism
Vancomycin
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Summary:Examples of chiral separations in counter-current chromatography (CCC) and centrifugal partition chromatography (CPC) are not numerous, due to the difficulty of finding chiral selectors highly selective in the liquid phase as well as a combination of solvents that does not destroy the selectivity and retains the capacity to elute chiral isomers of interest. New ideas and new chiral selectors generally come from other separation techniques, as will be highlighted in this review.
ISSN:0021-9673
DOI:10.1016/S0021-9673(00)00499-4