Efficacy of moxidectin 2 per cent gel against naturally acquired strongyle infections in horses, with particular reference to larval cyathostomes

The efficacy of moxidectin 2 per cent equine gel against naturally acquired strongyle infections was assessed in 18 ponies which had grazed on contaminated pasture before being housed for eight weeks. Twenty-four hours before the treatment, two randomly selected ponies were euthanased and their worm...

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Bibliographic Details
Published in:Veterinary record 2001-02, Vol.148 (5), p.138-141
Main Authors: Bairden, K, Brown, S R, McGoldrick, J, Parker, L D, Talty, P J
Format: Article
Language:English
Subjects:
Animals
Anthelmintics - pharmacology
Anthelmintics - therapeutic use
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Feces - parasitology
Female
Horses
Larva - drug effects
Larva - growth & development
Macrolides
Male
Strongyle Infections, Equine - drug therapy
Strongyle Infections, Equine - parasitology
Strongyloidea - drug effects
Strongyloidea - growth & development
Treatment Outcome
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Summary:The efficacy of moxidectin 2 per cent equine gel against naturally acquired strongyle infections was assessed in 18 ponies which had grazed on contaminated pasture before being housed for eight weeks. Twenty-four hours before the treatment, two randomly selected ponies were euthanased and their worm burdens were determined. Eight of the remaining 16 ponies were treated with moxidectin 2 per cent gel while the other eight were given a placebo gel. Eight weeks later the 16 animals were necropsied and their worm burdens established. A 100 per cent efficacy was recorded against adult and lumenal L4 cyathostomes and adult Strongylus and Triodontophorus species. Digest recoveries of larval cyathostomes indicated a 90.8 per cent (P
ISSN:0042-4900
DOI:10.1136/vr.148.5.138