The tify family previously known as ZIM

The ZIM domain was originally identified in the ZIM protein (BAA97679; Zinc-finger protein expressed in Inflorescence Meristem). Since then it has been found in other proteins and the corresponding genes have been grouped into a plant-specific family. However, the family lacks consistency in its cla...

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Bibliographic Details
Published in:Trends in plant science 2007-06, Vol.12 (6), p.239-244
Main Authors: Vanholme, Bartel, Grunewald, Wim, Bateman, Alex, Kohchi, Takayuki, Gheysen, Godelieve
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Arabidopsis Proteins - genetics
Arabidopsis Proteins - metabolism
Arabidopsis Proteins - physiology
Arabidopsis thaliana
Biological and medical sciences
Evolution, Molecular
flower primordia
Fundamental and applied biological sciences. Psychology
Genes. Genome
literature reviews
Models, Genetic
Molecular and cellular biology
Molecular genetics
Multigene Family
Phylogeny
plant biochemistry
plant proteins
Sequence Homology, Amino Acid
TIFY protein
transcription factors
Transcription Factors - genetics
Transcription Factors - metabolism
Transcription Factors - physiology
zinc finger motif
Zinc Fingers
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Description
Summary:The ZIM domain was originally identified in the ZIM protein (BAA97679; Zinc-finger protein expressed in Inflorescence Meristem). Since then it has been found in other proteins and the corresponding genes have been grouped into a plant-specific family. However, the family lacks consistency in its classification among different databases. Here, we try to clarify this incongruity by presenting an overview of the Arabidopsis proteins having this domain. The presented genome-wide survey can be seen as a start point to reveal the unknown function of these proteins. Furthermore, because of the confusing ZIM nomenclature being used at present, we propose to rename the domain and family as tify, after the most conserved amino acid motif characterizing the members of this family.
ISSN:1360-1385
1878-4372
DOI:10.1016/j.tplants.2007.04.004