Surface modification of resorcinarene based self-assembled solid lipid nanoparticles for drug targeting

Prolyl-bearing amphiphilic resorcinarenes, e.g. tetrakis(N-methylprolyl)tetraundecylcalix[4]resorcinarene, self-assemble as stable solid lipid nanoparticles; these fully characterized systems could be further functionalized at their surface with proteins, and interact with specific antibodies bound...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2007-01 (25), p.2605-2607
Main Authors: Ehrler, Stefan, Pieles, Uwe, Wirth-Heller, Amina, Shahgaldian, Patrick
Format: Article
Language:English
Subjects:
Calixarenes - chemistry
Drug Delivery Systems
Microscopy, Atomic Force
Microscopy, Electron, Scanning
Nanoparticles - chemistry
Particle Size
Phenylalanine - analogs & derivatives
Phenylalanine - chemistry
Serum Albumin, Bovine - chemistry
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Summary:Prolyl-bearing amphiphilic resorcinarenes, e.g. tetrakis(N-methylprolyl)tetraundecylcalix[4]resorcinarene, self-assemble as stable solid lipid nanoparticles; these fully characterized systems could be further functionalized at their surface with proteins, and interact with specific antibodies bound on a sensor surface.
ISSN:1359-7345
1364-548X
DOI:10.1039/b703106h