Anti-inflammatory effect of (+)-pinitol

In the carrageenin-induced paw oedema in rats, (+)-pinitol (2.5–10 mg/kg, i.p.), isolated from Abies pindrow leaves, showed a significant anti-inflammatory effect, the highest dose being comparable to phenylbutazone (100 mg/kg, i.p.).

Saved in:
Bibliographic Details
Published in:Fitoterapia 2001-02, Vol.72 (2), p.168-170
Main Authors: Singh, R.K., Pandey, B.L., Tripathi, M., Pandey, V.B.
Format: Article
Language:English
Subjects:
(+)-Pinitol
Abies pindrow
Animals
Anti-inflammatory activity
Anti-Inflammatory Agents - pharmacology
Biological and medical sciences
Carrageenan
Dose-Response Relationship, Drug
Edema - chemically induced
Edema - prevention & control
Female
General pharmacology
Inositol - analogs & derivatives
Inositol - pharmacology
Male
Medical sciences
Mice
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Plant Leaves
Plants, Medicinal
Rats
Rats, Wistar
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the carrageenin-induced paw oedema in rats, (+)-pinitol (2.5–10 mg/kg, i.p.), isolated from Abies pindrow leaves, showed a significant anti-inflammatory effect, the highest dose being comparable to phenylbutazone (100 mg/kg, i.p.).
ISSN:0367-326X
DOI:10.1016/S0367-326X(00)00267-7