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Theory of mind in schizophrenia: Meta-analysis
Mentalising impairment (an impaired ability to think about people in terms of their mental states) has frequently been associated with schizophrenia. To assess the magnitude of the deficit and analyse associated factors. Twenty-nine studies of mentalising in schizophrenia (combined n=1518), publishe...
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| Published in: | British journal of psychiatry 2007-07, Vol.191 (1), p.5-13 |
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| container_end_page | 13 |
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| container_title | British journal of psychiatry |
| container_volume | 191 |
| creator | Sprong, Mirjam Schothorst, Patricia Vos, Ellen Hox, Joop Van Engeland, Herman |
| description | Mentalising impairment (an impaired ability to think about people in terms of their mental states) has frequently been associated with schizophrenia.
To assess the magnitude of the deficit and analyse associated factors.
Twenty-nine studies of mentalising in schizophrenia (combined n=1518), published between January 1993 and May 2006, were included to estimate overall effect size. Study descriptors predicted to influence effect size were analysed using weighted regression-analysis techniques. Separate analyses were performed for symptom subgroups and task types.
The estimated overall effect size was large and statistically significant (d=-1.255, P |
| doi_str_mv | 10.1192/bjp.bp.107.035899 |
| format | article |
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To assess the magnitude of the deficit and analyse associated factors.
Twenty-nine studies of mentalising in schizophrenia (combined n=1518), published between January 1993 and May 2006, were included to estimate overall effect size. Study descriptors predicted to influence effect size were analysed using weighted regression-analysis techniques. Separate analyses were performed for symptom subgroups and task types.
The estimated overall effect size was large and statistically significant (d=-1.255, P<0.0001) and was not significantly affected by sample characteristics. All symptom subgroups showed significant mentalising impairment, but participants with symptoms of disorganisation were significantly more impaired than the other subgroups (P<0.01).
This meta-analysis showed significant and stable mentalising impairment in schizophrenia. The finding that patients in remission are also impaired favours the notion that mentalising impairment represents a possible trait marker of schizophrenia.</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.bp.107.035899</identifier><identifier>PMID: 17602119</identifier><identifier>CODEN: BJPYAJ</identifier><language>eng</language><publisher>England: RCP</publisher><subject>Adult ; Autism ; Child ; Child & adolescent psychiatry ; Child, Preschool ; Cognition ; Cognition Disorders - epidemiology ; Cognition Disorders - psychology ; Deception ; Effect Modifier, Epidemiologic ; Humans ; Mental disorders ; Mental states ; Meta-analysis ; Psychiatry ; Psychosis ; Quantitative psychology ; Remission ; Remission (Medicine) ; Schizophrenia ; Schizophrenia - classification ; Schizophrenia - epidemiology ; Schizophrenic Psychology ; Severity of Illness Index ; Social Perception ; Statistical analysis ; Statistics as Topic ; Studies ; Systematic review ; Task analysis ; Theory of mind</subject><ispartof>British journal of psychiatry, 2007-07, Vol.191 (1), p.5-13</ispartof><rights>Copyright © Royal College of Psychiatrists, 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c334t-bd815a5e3722b88ad46ad34242298778e999ffddbe395d2034faf25f425068d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2315591691/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2315591691?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,12846,21394,21395,27924,27925,30999,31000,33611,33612,34530,34531,43733,44115,74093,74511</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17602119$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sprong, Mirjam</creatorcontrib><creatorcontrib>Schothorst, Patricia</creatorcontrib><creatorcontrib>Vos, Ellen</creatorcontrib><creatorcontrib>Hox, Joop</creatorcontrib><creatorcontrib>Van Engeland, Herman</creatorcontrib><title>Theory of mind in schizophrenia: Meta-analysis</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>Mentalising impairment (an impaired ability to think about people in terms of their mental states) has frequently been associated with schizophrenia.
To assess the magnitude of the deficit and analyse associated factors.
Twenty-nine studies of mentalising in schizophrenia (combined n=1518), published between January 1993 and May 2006, were included to estimate overall effect size. Study descriptors predicted to influence effect size were analysed using weighted regression-analysis techniques. Separate analyses were performed for symptom subgroups and task types.
The estimated overall effect size was large and statistically significant (d=-1.255, P<0.0001) and was not significantly affected by sample characteristics. All symptom subgroups showed significant mentalising impairment, but participants with symptoms of disorganisation were significantly more impaired than the other subgroups (P<0.01).
This meta-analysis showed significant and stable mentalising impairment in schizophrenia. The finding that patients in remission are also impaired favours the notion that mentalising impairment represents a possible trait marker of schizophrenia.</description><subject>Adult</subject><subject>Autism</subject><subject>Child</subject><subject>Child & adolescent psychiatry</subject><subject>Child, Preschool</subject><subject>Cognition</subject><subject>Cognition Disorders - epidemiology</subject><subject>Cognition Disorders - psychology</subject><subject>Deception</subject><subject>Effect Modifier, Epidemiologic</subject><subject>Humans</subject><subject>Mental disorders</subject><subject>Mental states</subject><subject>Meta-analysis</subject><subject>Psychiatry</subject><subject>Psychosis</subject><subject>Quantitative psychology</subject><subject>Remission</subject><subject>Remission (Medicine)</subject><subject>Schizophrenia</subject><subject>Schizophrenia - classification</subject><subject>Schizophrenia - epidemiology</subject><subject>Schizophrenic Psychology</subject><subject>Severity of Illness Index</subject><subject>Social Perception</subject><subject>Statistical analysis</subject><subject>Statistics as Topic</subject><subject>Studies</subject><subject>Systematic review</subject><subject>Task analysis</subject><subject>Theory of mind</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><sourceid>ALSLI</sourceid><sourceid>HEHIP</sourceid><sourceid>M2R</sourceid><sourceid>M2S</sourceid><recordid>eNqFkE9LxDAQxYMo7rr6AbxoQfDWmkmapvEmi_9gxct6DmmT2izdtiZbpH56I10QvHgaHvzem5mH0DngBECQm2LTJ0WfAOYJpiwX4gDNIeUkhjRjh2iOMeYxEIZn6MT7TZA0JfwYzYBnmISIOUrWtencGHVVtLWtjmwb-bK2X11fO9NadRu9mJ2KVaua0Vt_io4q1Xhztp8L9PZwv14-xavXx-fl3SouKU13caFzYIoZygkp8lzpNFM67E4JETnnuRFCVJXWhaGCaRLOqlRFWJWGW7NcE7pA11Nu77qPwfid3FpfmqZRrekGLznOGGfp_yDjQDEVeQCv_oCbbnDhLS8JBcYEZAICBRNVus57ZyrZO7tVbpSA5U_nMnQuiz5ILqfOg-dinzwUW6N_HfuSA3A5AbV9rz-tM9KVvR_LWoIACZLRb33HhgE</recordid><startdate>20070701</startdate><enddate>20070701</enddate><creator>Sprong, Mirjam</creator><creator>Schothorst, Patricia</creator><creator>Vos, Ellen</creator><creator>Hox, Joop</creator><creator>Van Engeland, Herman</creator><general>RCP</general><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7TK</scope><scope>7XB</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>M2M</scope><scope>M2O</scope><scope>M2R</scope><scope>M2S</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20070701</creationdate><title>Theory of mind in schizophrenia: Meta-analysis</title><author>Sprong, Mirjam ; 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To assess the magnitude of the deficit and analyse associated factors.
Twenty-nine studies of mentalising in schizophrenia (combined n=1518), published between January 1993 and May 2006, were included to estimate overall effect size. Study descriptors predicted to influence effect size were analysed using weighted regression-analysis techniques. Separate analyses were performed for symptom subgroups and task types.
The estimated overall effect size was large and statistically significant (d=-1.255, P<0.0001) and was not significantly affected by sample characteristics. All symptom subgroups showed significant mentalising impairment, but participants with symptoms of disorganisation were significantly more impaired than the other subgroups (P<0.01).
This meta-analysis showed significant and stable mentalising impairment in schizophrenia. The finding that patients in remission are also impaired favours the notion that mentalising impairment represents a possible trait marker of schizophrenia.</abstract><cop>England</cop><pub>RCP</pub><pmid>17602119</pmid><doi>10.1192/bjp.bp.107.035899</doi><tpages>9</tpages></addata></record> |
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| ispartof | British journal of psychiatry, 2007-07, Vol.191 (1), p.5-13 |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); Cambridge Journals Online; Social Science Premium Collection (Proquest) (PQ_SDU_P3); Sociology Collection |
| subjects | Adult Autism Child Child & adolescent psychiatry Child, Preschool Cognition Cognition Disorders - epidemiology Cognition Disorders - psychology Deception Effect Modifier, Epidemiologic Humans Mental disorders Mental states Meta-analysis Psychiatry Psychosis Quantitative psychology Remission Remission (Medicine) Schizophrenia Schizophrenia - classification Schizophrenia - epidemiology Schizophrenic Psychology Severity of Illness Index Social Perception Statistical analysis Statistics as Topic Studies Systematic review Task analysis Theory of mind |
| title | Theory of mind in schizophrenia: Meta-analysis |
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