Loading…
Apnoea of prematurity and arousal from sleep
The incidence of sudden infant death syndrome (SIDS) has been found to be consistently higher in preterm and low birth weight infants than in infants born at term and this increase is inversely related to gestational age. The incidence and severity of apnoea of prematurity, are also inversely relate...
Saved in:
| Published in: | Early human development 2001-03, Vol.61 (2), p.119-133 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433 |
| container_end_page | 133 |
| container_issue | 2 |
| container_start_page | 119 |
| container_title | Early human development |
| container_volume | 61 |
| creator | Horne, Rosemary S.C. Andrew, Sarah Mitchell, Kristy Sly, David J. Cranage, Susan M. Chau, Bonnie Adamson, T.Michael |
| description | The incidence of sudden infant death syndrome (SIDS) has been found to be consistently higher in preterm and low birth weight infants than in infants born at term and this increase is inversely related to gestational age. The incidence and severity of apnoea of prematurity, are also inversely related to gestational age. The aim of this study was to investigate whether a neonatal history of apnoea/bradycardia affected the maturation of arousal responses. Twenty-five premature infants were studied. A perinatal risk score was determined for each infant and infants were divided into those with a neonatal history of apnoea/bradycardia (
n=16) and those without (
n=9). All infants were studied using daytime polysomnography on three occasions: (a) a preterm study around 36 weeks gestation, (b) within 3 weeks of term, and (c) 2–3 months post-term. Multiple measurements of arousal threshold (cmH
2O) in response to air-jet stimulation applied alternately to the nares were made in both active sleep (AS) and quiet sleep (QS). Arousal thresholds were elevated in apnoeic infants compared to control infants in both AS (
P |
| doi_str_mv | 10.1016/S0378-3782(00)00129-8 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70662576</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0378378200001298</els_id><sourcerecordid>70662576</sourcerecordid><originalsourceid>FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433</originalsourceid><addsrcrecordid>eNqFkEtLxDAQgIMo7rr6E5SCIApWJ0k3TU-yLL5gwYN6Dmk6gUpfJq2w_97sblmPHmbm8s3rI-Scwh0FKu7fgacyDsGuAW4AKMtieUCmVKYsFoyzQzLdIxNy4v0XAMxlBsdkQikLRJpMye2ia1rUUWujzmGt-8GV_TrSTRFp1w5eV5F1bR35CrE7JUdWVx7Pxjojn0-PH8uXePX2_LpcrGLDZdbHyBC55pIKUSRAbYiQM04pxzkU2rAcaFJokQubS20NGG4Mt2C5RZFwPiNXu7mda78H9L2qS2-wqnSD4SaVghBsnooAznegca33Dq3qXFlrt1YU1EaT2mpSGwcKQG01KRn6LsYFQ15j8dc1egnA5Qhob3RlnW5M6feczNLwQaAedhQGGT8lOuVNiY3BonRoelW05T-H_AJo-YKZ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70662576</pqid></control><display><type>article</type><title>Apnoea of prematurity and arousal from sleep</title><source>Elsevier</source><creator>Horne, Rosemary S.C. ; Andrew, Sarah ; Mitchell, Kristy ; Sly, David J. ; Cranage, Susan M. ; Chau, Bonnie ; Adamson, T.Michael</creator><creatorcontrib>Horne, Rosemary S.C. ; Andrew, Sarah ; Mitchell, Kristy ; Sly, David J. ; Cranage, Susan M. ; Chau, Bonnie ; Adamson, T.Michael</creatorcontrib><description>The incidence of sudden infant death syndrome (SIDS) has been found to be consistently higher in preterm and low birth weight infants than in infants born at term and this increase is inversely related to gestational age. The incidence and severity of apnoea of prematurity, are also inversely related to gestational age. The aim of this study was to investigate whether a neonatal history of apnoea/bradycardia affected the maturation of arousal responses. Twenty-five premature infants were studied. A perinatal risk score was determined for each infant and infants were divided into those with a neonatal history of apnoea/bradycardia (
n=16) and those without (
n=9). All infants were studied using daytime polysomnography on three occasions: (a) a preterm study around 36 weeks gestation, (b) within 3 weeks of term, and (c) 2–3 months post-term. Multiple measurements of arousal threshold (cmH
2O) in response to air-jet stimulation applied alternately to the nares were made in both active sleep (AS) and quiet sleep (QS). Arousal thresholds were elevated in apnoeic infants compared to control infants in both AS (
P<0.05) and QS (
P<0.001) at the term study and in QS at 2–3 months post-term (
P<0.01). In addition, arousal thresholds were positively correlated with perinatal risk score in both sleep states, in all studies, with the exception of AS at 2–3 months when all infants were readily arouseable. We conclude that a history of prematurity with neonatal apnoea has a persisting effect on decreasing arousabilty from sleep and these infants may be at increased risk for SIDS.</description><identifier>ISSN: 0378-3782</identifier><identifier>EISSN: 1872-6232</identifier><identifier>DOI: 10.1016/S0378-3782(00)00129-8</identifier><identifier>PMID: 11223274</identifier><identifier>CODEN: EHDEDN</identifier><language>eng</language><publisher>Lausanne: Elsevier Ireland Ltd</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Apnea - physiopathology ; Apnoea of prematurity ; Arousal ; Arousal - physiology ; Biological and medical sciences ; Birth Weight ; Electrocardiography ; Electroencephalography ; Electromyography ; Electrooculography ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Infant, Premature ; Intensive care medicine ; Male ; Medical sciences ; Premature infants ; Risk Factors ; SIDS ; Sleep ; Sudden Infant Death - etiology</subject><ispartof>Early human development, 2001-03, Vol.61 (2), p.119-133</ispartof><rights>2001 Elsevier Science Ireland Ltd</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433</citedby><cites>FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=897014$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11223274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Horne, Rosemary S.C.</creatorcontrib><creatorcontrib>Andrew, Sarah</creatorcontrib><creatorcontrib>Mitchell, Kristy</creatorcontrib><creatorcontrib>Sly, David J.</creatorcontrib><creatorcontrib>Cranage, Susan M.</creatorcontrib><creatorcontrib>Chau, Bonnie</creatorcontrib><creatorcontrib>Adamson, T.Michael</creatorcontrib><title>Apnoea of prematurity and arousal from sleep</title><title>Early human development</title><addtitle>Early Hum Dev</addtitle><description>The incidence of sudden infant death syndrome (SIDS) has been found to be consistently higher in preterm and low birth weight infants than in infants born at term and this increase is inversely related to gestational age. The incidence and severity of apnoea of prematurity, are also inversely related to gestational age. The aim of this study was to investigate whether a neonatal history of apnoea/bradycardia affected the maturation of arousal responses. Twenty-five premature infants were studied. A perinatal risk score was determined for each infant and infants were divided into those with a neonatal history of apnoea/bradycardia (
n=16) and those without (
n=9). All infants were studied using daytime polysomnography on three occasions: (a) a preterm study around 36 weeks gestation, (b) within 3 weeks of term, and (c) 2–3 months post-term. Multiple measurements of arousal threshold (cmH
2O) in response to air-jet stimulation applied alternately to the nares were made in both active sleep (AS) and quiet sleep (QS). Arousal thresholds were elevated in apnoeic infants compared to control infants in both AS (
P<0.05) and QS (
P<0.001) at the term study and in QS at 2–3 months post-term (
P<0.01). In addition, arousal thresholds were positively correlated with perinatal risk score in both sleep states, in all studies, with the exception of AS at 2–3 months when all infants were readily arouseable. We conclude that a history of prematurity with neonatal apnoea has a persisting effect on decreasing arousabilty from sleep and these infants may be at increased risk for SIDS.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Apnea - physiopathology</subject><subject>Apnoea of prematurity</subject><subject>Arousal</subject><subject>Arousal - physiology</subject><subject>Biological and medical sciences</subject><subject>Birth Weight</subject><subject>Electrocardiography</subject><subject>Electroencephalography</subject><subject>Electromyography</subject><subject>Electrooculography</subject><subject>Emergency and intensive care: neonates and children. Prematurity. Sudden death</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Premature infants</subject><subject>Risk Factors</subject><subject>SIDS</subject><subject>Sleep</subject><subject>Sudden Infant Death - etiology</subject><issn>0378-3782</issn><issn>1872-6232</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNqFkEtLxDAQgIMo7rr6E5SCIApWJ0k3TU-yLL5gwYN6Dmk6gUpfJq2w_97sblmPHmbm8s3rI-Scwh0FKu7fgacyDsGuAW4AKMtieUCmVKYsFoyzQzLdIxNy4v0XAMxlBsdkQikLRJpMye2ia1rUUWujzmGt-8GV_TrSTRFp1w5eV5F1bR35CrE7JUdWVx7Pxjojn0-PH8uXePX2_LpcrGLDZdbHyBC55pIKUSRAbYiQM04pxzkU2rAcaFJokQubS20NGG4Mt2C5RZFwPiNXu7mda78H9L2qS2-wqnSD4SaVghBsnooAznegca33Dq3qXFlrt1YU1EaT2mpSGwcKQG01KRn6LsYFQ15j8dc1egnA5Qhob3RlnW5M6feczNLwQaAedhQGGT8lOuVNiY3BonRoelW05T-H_AJo-YKZ</recordid><startdate>20010301</startdate><enddate>20010301</enddate><creator>Horne, Rosemary S.C.</creator><creator>Andrew, Sarah</creator><creator>Mitchell, Kristy</creator><creator>Sly, David J.</creator><creator>Cranage, Susan M.</creator><creator>Chau, Bonnie</creator><creator>Adamson, T.Michael</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010301</creationdate><title>Apnoea of prematurity and arousal from sleep</title><author>Horne, Rosemary S.C. ; Andrew, Sarah ; Mitchell, Kristy ; Sly, David J. ; Cranage, Susan M. ; Chau, Bonnie ; Adamson, T.Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Apnea - physiopathology</topic><topic>Apnoea of prematurity</topic><topic>Arousal</topic><topic>Arousal - physiology</topic><topic>Biological and medical sciences</topic><topic>Birth Weight</topic><topic>Electrocardiography</topic><topic>Electroencephalography</topic><topic>Electromyography</topic><topic>Electrooculography</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Premature infants</topic><topic>Risk Factors</topic><topic>SIDS</topic><topic>Sleep</topic><topic>Sudden Infant Death - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Horne, Rosemary S.C.</creatorcontrib><creatorcontrib>Andrew, Sarah</creatorcontrib><creatorcontrib>Mitchell, Kristy</creatorcontrib><creatorcontrib>Sly, David J.</creatorcontrib><creatorcontrib>Cranage, Susan M.</creatorcontrib><creatorcontrib>Chau, Bonnie</creatorcontrib><creatorcontrib>Adamson, T.Michael</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Early human development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Horne, Rosemary S.C.</au><au>Andrew, Sarah</au><au>Mitchell, Kristy</au><au>Sly, David J.</au><au>Cranage, Susan M.</au><au>Chau, Bonnie</au><au>Adamson, T.Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Apnoea of prematurity and arousal from sleep</atitle><jtitle>Early human development</jtitle><addtitle>Early Hum Dev</addtitle><date>2001-03-01</date><risdate>2001</risdate><volume>61</volume><issue>2</issue><spage>119</spage><epage>133</epage><pages>119-133</pages><issn>0378-3782</issn><eissn>1872-6232</eissn><coden>EHDEDN</coden><abstract>The incidence of sudden infant death syndrome (SIDS) has been found to be consistently higher in preterm and low birth weight infants than in infants born at term and this increase is inversely related to gestational age. The incidence and severity of apnoea of prematurity, are also inversely related to gestational age. The aim of this study was to investigate whether a neonatal history of apnoea/bradycardia affected the maturation of arousal responses. Twenty-five premature infants were studied. A perinatal risk score was determined for each infant and infants were divided into those with a neonatal history of apnoea/bradycardia (
n=16) and those without (
n=9). All infants were studied using daytime polysomnography on three occasions: (a) a preterm study around 36 weeks gestation, (b) within 3 weeks of term, and (c) 2–3 months post-term. Multiple measurements of arousal threshold (cmH
2O) in response to air-jet stimulation applied alternately to the nares were made in both active sleep (AS) and quiet sleep (QS). Arousal thresholds were elevated in apnoeic infants compared to control infants in both AS (
P<0.05) and QS (
P<0.001) at the term study and in QS at 2–3 months post-term (
P<0.01). In addition, arousal thresholds were positively correlated with perinatal risk score in both sleep states, in all studies, with the exception of AS at 2–3 months when all infants were readily arouseable. We conclude that a history of prematurity with neonatal apnoea has a persisting effect on decreasing arousabilty from sleep and these infants may be at increased risk for SIDS.</abstract><cop>Lausanne</cop><cop>New York,NY</cop><cop>Amsterdam</cop><pub>Elsevier Ireland Ltd</pub><pmid>11223274</pmid><doi>10.1016/S0378-3782(00)00129-8</doi><tpages>15</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-3782 |
| ispartof | Early human development, 2001-03, Vol.61 (2), p.119-133 |
| issn | 0378-3782 1872-6232 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70662576 |
| source | Elsevier |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Apnea - physiopathology Apnoea of prematurity Arousal Arousal - physiology Biological and medical sciences Birth Weight Electrocardiography Electroencephalography Electromyography Electrooculography Emergency and intensive care: neonates and children. Prematurity. Sudden death Female Gestational Age Humans Infant, Newborn Infant, Premature Intensive care medicine Male Medical sciences Premature infants Risk Factors SIDS Sleep Sudden Infant Death - etiology |
| title | Apnoea of prematurity and arousal from sleep |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T21%3A26%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Apnoea%20of%20prematurity%20and%20arousal%20from%20sleep&rft.jtitle=Early%20human%20development&rft.au=Horne,%20Rosemary%20S.C.&rft.date=2001-03-01&rft.volume=61&rft.issue=2&rft.spage=119&rft.epage=133&rft.pages=119-133&rft.issn=0378-3782&rft.eissn=1872-6232&rft.coden=EHDEDN&rft_id=info:doi/10.1016/S0378-3782(00)00129-8&rft_dat=%3Cproquest_cross%3E70662576%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c389t-e2ee3a38166d401f40101f93113e50dac2b014da6b6fb8afc0c3cc3f0f3fe6433%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=70662576&rft_id=info:pmid/11223274&rfr_iscdi=true |