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A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies
Near-infrared spectroscopy (NIRS) is a fast and non-destructive analytical method. Associated with chemometrics, it becomes a powerful tool for the pharmaceutical industry. Indeed, NIRS is suitable for analysis of solid, liquid and biotechnological pharmaceutical forms. Moreover, NIRS can be impleme...
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| Published in: | Journal of pharmaceutical and biomedical analysis 2007-07, Vol.44 (3), p.683-700 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c524t-264b7f254e43aa277d8b367e83c04b01aaaa386c26500a05fcb9585019b454293 |
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| cites | cdi_FETCH-LOGICAL-c524t-264b7f254e43aa277d8b367e83c04b01aaaa386c26500a05fcb9585019b454293 |
| container_end_page | 700 |
| container_issue | 3 |
| container_start_page | 683 |
| container_title | Journal of pharmaceutical and biomedical analysis |
| container_volume | 44 |
| creator | Roggo, Yves Chalus, Pascal Maurer, Lene Lema-Martinez, Carmen Edmond, Aurélie Jent, Nadine |
| description | Near-infrared spectroscopy (NIRS) is a fast and non-destructive analytical method. Associated with chemometrics, it becomes a powerful tool for the pharmaceutical industry. Indeed, NIRS is suitable for analysis of solid, liquid and biotechnological pharmaceutical forms. Moreover, NIRS can be implemented during pharmaceutical development, in production for process monitoring or in quality control laboratories.This review focuses on chemometric techniques and pharmaceutical NIRS applications. The following topics are covered: qualitative analyses, quantitative methods and on-line applications. Theoretical and practical aspects are described with pharmaceutical examples of NIRS applications. |
| doi_str_mv | 10.1016/j.jpba.2007.03.023 |
| format | article |
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| fulltext | fulltext |
| identifier | ISSN: 0731-7085 |
| ispartof | Journal of pharmaceutical and biomedical analysis, 2007-07, Vol.44 (3), p.683-700 |
| issn | 0731-7085 1873-264X |
| language | eng |
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| source | ScienceDirect Freedom Collection |
| subjects | Analysis Analytical, structural and metabolic biochemistry Biological and medical sciences Chemometrics Drug Design Fundamental and applied biological sciences. Psychology General pharmacology Humans Identification Medical sciences Near infrared spectroscopy On-line Pharmaceutical Preparations - analysis Pharmaceuticals Pharmacology. Drug treatments Qualification Quality control Quantification Spectroscopy, Near-Infrared Technology, Pharmaceutical - methods Technology, Pharmaceutical - trends |
| title | A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies |
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