Prevalence and common genotypes of HCV infection in Sudanese patients with hepatosplenic schistosomiasis

A cross‐sectional hospital based study was carried out at the National Center for Gastrointestinal and Liver Disease in Khartoum, Sudan to determine the prevalence, common genotypes and risk factors for hepatitis C virus infection in Sudanese patients with hepatosplenic schistosomiasis. A total of 1...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical virology 2007-09, Vol.79 (9), p.1322-1324
Main Authors: Mudawi, H.M.Y., Smith, H.M., Fletcher, I.A., Fedail, S.S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Animals
Biological and medical sciences
Cross-Sectional Studies
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Genotype
Hepacivirus - classification
Hepacivirus - genetics
Hepacivirus - immunology
Hepatitis C - complications
Hepatitis C - epidemiology
Hepatitis C - virology
Hepatitis C Antibodies - immunology
Hepatitis C virus
hepatosplenic schistosomiasis
Human viral diseases
Humans
Infectious diseases
Liver Diseases, Parasitic - complications
Male
Medical sciences
Microbiology
Middle Aged
Miscellaneous
parenteral antischistosomal therapy
Prevalence
Schistosoma
Schistosomiasis mansoni - complications
Seroepidemiologic Studies
Splenic Diseases - complications
Sudan - epidemiology
Viral diseases
Virology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A cross‐sectional hospital based study was carried out at the National Center for Gastrointestinal and Liver Disease in Khartoum, Sudan to determine the prevalence, common genotypes and risk factors for hepatitis C virus infection in Sudanese patients with hepatosplenic schistosomiasis. A total of 176 patients with hepatosplenic schistosomiasis were tested for HCV antibodies and 4.5% of the samples were reactive. PCR was positive in 2.3% of cases and genotype 4 was the major genotype isolated with subtypes 4, 4e, and 4c/4d. It is concluded that HCV was of low seroprevalence in the study population and that parenteral antischistosomal therapy was not a significant risk factor in transmission of infection in the Sudan. J. Med. Virol. 79:1322–1324, 2007. © Wiley‐Liss, Inc.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.20865