Therapeutic possibilities of plasmonically heated gold nanoparticles

Nanoparticles of gold, which are in the size range 10–100 nm, undergo a plasmon resonance with light. This is a process whereby the electrons of the gold resonate in response to incoming radiation causing them to both absorb and scatter light. This effect can be harnessed to either destroy tissue by...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 2006-02, Vol.24 (2), p.62-67
Main Authors: Pissuwan, Dakrong, Valenzuela, Stella M., Cortie, Michael B.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
Gold - chemistry
Gold - therapeutic use
Health. Pharmaceutical industry
Hot Temperature
Immunoconjugates - chemistry
Immunoconjugates - therapeutic use
Immunologic Factors - chemistry
Immunologic Factors - therapeutic use
Industrial applications and implications. Economical aspects
Miscellaneous
Nanostructures
Neoplasms - drug therapy
Phototherapy - methods
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Summary:Nanoparticles of gold, which are in the size range 10–100 nm, undergo a plasmon resonance with light. This is a process whereby the electrons of the gold resonate in response to incoming radiation causing them to both absorb and scatter light. This effect can be harnessed to either destroy tissue by local heating or release payload molecules of therapeutic importance. Gold nanoparticles can also be conjugated to biologically active moieties, providing possibilities for targeting to particular tissues. Here, we review the progress made in the exploitation of the plasmon resonance of gold nanoparticles in photo-thermal therapeutic medicine.
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2005.12.004