Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus

Circadian rhythm pervades in many aspects of the biological processes including basic cellular functions. Here we examined the circadian gene expression of two forms of 90 kDa heat shock proteins referred to HSP86 and HSP84 in the mouse suprachiasmatic nucleus, the circadian center. In both light-da...

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Published in:Biomedical Research 2008, Vol.29(2), pp.93-98
Main Authors: FUKUYAMA, Tsuyoshi, DOI, Masao, MATSUO, Masahiro, NISHINAGA, Hiromi, MIYAKE, Shigeru, OKAMURA, Hitoshi
Format: Article
Language:English
Subjects:
Animals
Biological Clocks - genetics
Circadian Rhythm - genetics
Gene Expression Regulation - physiology
HSP90 Heat-Shock Proteins - biosynthesis
HSP90 Heat-Shock Proteins - genetics
Male
Mice
Mice, Inbred C57BL
Prosencephalon - chemistry
Prosencephalon - metabolism
Suprachiasmatic Nucleus - chemistry
Suprachiasmatic Nucleus - metabolism
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cited_by cdi_FETCH-LOGICAL-c577t-363005d66b3760804cbe6cee4fb9af4fbad4c940a20938ab36b16a4d74fc89d43
cites cdi_FETCH-LOGICAL-c577t-363005d66b3760804cbe6cee4fb9af4fbad4c940a20938ab36b16a4d74fc89d43
container_end_page 98
container_issue 2
container_start_page 93
container_title Biomedical Research
container_volume 29
creator FUKUYAMA, Tsuyoshi
DOI, Masao
MATSUO, Masahiro
NISHINAGA, Hiromi
MIYAKE, Shigeru
OKAMURA, Hitoshi
description Circadian rhythm pervades in many aspects of the biological processes including basic cellular functions. Here we examined the circadian gene expression of two forms of 90 kDa heat shock proteins referred to HSP86 and HSP84 in the mouse suprachiasmatic nucleus, the circadian center. In both light-dark, and constant dark conditions, Hsp86 mRNA showed an overt circadian rhythm showing a peak at (subjective) night and a trough at (subjective) day. Hsp84 mRNA also showed the similar expression profile, but the amplitude was weaker. These results indicate that gene expression of molecular chaperone such as Hsp86 and Hsp84 are regulated by the circadian clock.
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source J-STAGE (Japan Science & Technology Information Aggregator, Electronic) - Open Access English articles
subjects Animals
Biological Clocks - genetics
Circadian Rhythm - genetics
Gene Expression Regulation - physiology
HSP90 Heat-Shock Proteins - biosynthesis
HSP90 Heat-Shock Proteins - genetics
Male
Mice
Mice, Inbred C57BL
Prosencephalon - chemistry
Prosencephalon - metabolism
Suprachiasmatic Nucleus - chemistry
Suprachiasmatic Nucleus - metabolism
title Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus
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