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Prognosis of congenital tracheoesophageal fistula with esophageal atresia on the basis of gap length
Congenital tracheoesophageal fistula (TEF) with esophageal atresia (EA) is not an uncommon disease of newborns. Several classifications have been advocated for predicting the outcomes of these patients but all are physiological and concentrated on associated medical condition that influences surviva...
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Published in: | Pediatric surgery international 2007-08, Vol.23 (8), p.767-771 |
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description | Congenital tracheoesophageal fistula (TEF) with esophageal atresia (EA) is not an uncommon disease of newborns. Several classifications have been advocated for predicting the outcomes of these patients but all are physiological and concentrated on associated medical condition that influences survival. We emphasize a new classification on the basis of gap between two esophageal pouches to define the magnitude of surgical problems in the primary repair and correlate them with the outcomes in terms of anastomotic leak, esophageal stricture and mortality, keeping other prognostic factors constant. A total of 50 cases of congenital TEF with EA were included and all underwent primary esophageal anastomosis after the ligation of TEF. The gap between the two pouches was meticulously measured intraoperatively using a vernier caliper before the ligation of TEF, and patients were divided into four groups on the basis of gap length. Group A, where gap length was >3.5 cm (ultralong), group B where gap length was 2.1-3.5 cm (long gap), group C where gap length was >1 cm but not more than 2 cm (intermediate group) and group D, where the gap between two esophageal pouches was 1 cm or less (short gap). The incidence of anastomotic leak was 80, 50, 28, 10.5% and the incidence of esophageal stricture was 100, 75, 22.5, 19% after successful primary repair, respectively, in groups A, B, C and D. The mortality was highest in group A (80%) followed by group B (50%) and 22% in group C and least 15.6% in group D. The incidences of esophageal leak and mortality were found to be statistically significant. This classification which is based on easily measurable criteria provides a useful method to predict morbidity, long-term outcome and mortality of EA with TEF surgery. |
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Several classifications have been advocated for predicting the outcomes of these patients but all are physiological and concentrated on associated medical condition that influences survival. We emphasize a new classification on the basis of gap between two esophageal pouches to define the magnitude of surgical problems in the primary repair and correlate them with the outcomes in terms of anastomotic leak, esophageal stricture and mortality, keeping other prognostic factors constant. A total of 50 cases of congenital TEF with EA were included and all underwent primary esophageal anastomosis after the ligation of TEF. The gap between the two pouches was meticulously measured intraoperatively using a vernier caliper before the ligation of TEF, and patients were divided into four groups on the basis of gap length. Group A, where gap length was >3.5 cm (ultralong), group B where gap length was 2.1-3.5 cm (long gap), group C where gap length was >1 cm but not more than 2 cm (intermediate group) and group D, where the gap between two esophageal pouches was 1 cm or less (short gap). The incidence of anastomotic leak was 80, 50, 28, 10.5% and the incidence of esophageal stricture was 100, 75, 22.5, 19% after successful primary repair, respectively, in groups A, B, C and D. The mortality was highest in group A (80%) followed by group B (50%) and 22% in group C and least 15.6% in group D. The incidences of esophageal leak and mortality were found to be statistically significant. This classification which is based on easily measurable criteria provides a useful method to predict morbidity, long-term outcome and mortality of EA with TEF surgery.</description><identifier>ISSN: 0179-0358</identifier><identifier>EISSN: 1437-9813</identifier><identifier>DOI: 10.1007/s00383-007-1964-0</identifier><identifier>PMID: 17579871</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Anastomosis, Surgical ; Body Weights and Measures ; Esophageal Atresia - complications ; Esophageal Atresia - surgery ; Esophagus - surgery ; Female ; Humans ; Infant, Newborn ; Male ; Prognosis ; Tracheoesophageal Fistula - classification ; Tracheoesophageal Fistula - complications ; Tracheoesophageal Fistula - surgery</subject><ispartof>Pediatric surgery international, 2007-08, Vol.23 (8), p.767-771</ispartof><rights>Springer-Verlag 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c398t-def3253c09fc0f2c6e196ee605f50d986624c5692ebf5fc18553cdd1597d225b3</citedby><cites>FETCH-LOGICAL-c398t-def3253c09fc0f2c6e196ee605f50d986624c5692ebf5fc18553cdd1597d225b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17579871$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Upadhyaya, Vijay D</creatorcontrib><creatorcontrib>Gangopadhyaya, A N</creatorcontrib><creatorcontrib>Gupta, D K</creatorcontrib><creatorcontrib>Sharma, S P</creatorcontrib><creatorcontrib>Kumar, Vijayendra</creatorcontrib><creatorcontrib>Pandey, Anand</creatorcontrib><creatorcontrib>Upadhyaya, Ashish D</creatorcontrib><title>Prognosis of congenital tracheoesophageal fistula with esophageal atresia on the basis of gap length</title><title>Pediatric surgery international</title><addtitle>Pediatr Surg Int</addtitle><description>Congenital tracheoesophageal fistula (TEF) with esophageal atresia (EA) is not an uncommon disease of newborns. 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subjects | Anastomosis, Surgical Body Weights and Measures Esophageal Atresia - complications Esophageal Atresia - surgery Esophagus - surgery Female Humans Infant, Newborn Male Prognosis Tracheoesophageal Fistula - classification Tracheoesophageal Fistula - complications Tracheoesophageal Fistula - surgery |
title | Prognosis of congenital tracheoesophageal fistula with esophageal atresia on the basis of gap length |
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