Synovial sarcoma in children. A single centre experience

Synovial sarcoma (SS) is a rare disease in the paediatric population, predominating in adolescents. Surgery remains the best treatment strategy for resectable cases. Adjuvant chemotherapy or radiotherapy can be used but have not proven efficacy. Metastatic disease and unsuccessful surgery are major...

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Bibliographic Details
Published in:Clinical & translational oncology 2007-07, Vol.9 (7), p.468-470
Main Authors: Moreno Martín-Retortillo, L, Andrés Moreno, M M, Cañete Nieto, A, Castel Sánchez, V
Format: Article
Language:English
Subjects:
Adolescent
Chemotherapy, Adjuvant
Child
Female
Humans
Lower Extremity
Male
Neoplasm Staging
Prognosis
Radiotherapy, Adjuvant
Sarcoma, Synovial - diagnosis
Sarcoma, Synovial - pathology
Sarcoma, Synovial - therapy
Treatment Outcome
Upper Extremity
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Summary:Synovial sarcoma (SS) is a rare disease in the paediatric population, predominating in adolescents. Surgery remains the best treatment strategy for resectable cases. Adjuvant chemotherapy or radiotherapy can be used but have not proven efficacy. Metastatic disease and unsuccessful surgery are major prognostic factors. We describe four cases in children aged 7-13 years old. All of them were affected by SS of upper and lower limbs, and had satisfactory resections with different outcomes in spite of receiving diverse chemotherapy regimens. One of them is at the moment under treatment for relapse, two are disease-free and another died after metastatic disease.
ISSN:1699-048X
1699-3055
DOI:10.1007/s12094-007-0087-3