Appendectomy, tonsillectomy, and risk of inflammatory bowel disease : a case control study in iran

There is some controversy about the prevalence of appendectomy and tonsillectomy among patients with Crohn's disease and a lower rate of appendectomy among patients with ulcerative colitis (UC). The objective of this study was to elucidate the role of appendectomy and tonsillectomy in Iranian p...

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Bibliographic Details
Published in:International journal of colorectal disease 2006-03, Vol.21 (2), p.155-159
Main Authors: FIROUZI, Farzad, BAHARI, Ali, AGHAZADEH, Rahim, MOHAMMAD REZA ZALI
Format: Article
Language:English
Subjects:
Adult
Appendectomy - adverse effects
Biological and medical sciences
Colitis, Ulcerative - epidemiology
Colitis, Ulcerative - etiology
Crohn Disease - epidemiology
Crohn Disease - etiology
Female
Follow-Up Studies
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Inflammatory bowel disease
Iran - epidemiology
Male
Medical sciences
Other diseases. Semiology
Prevalence
Retrospective Studies
Risk Factors
Stomach, duodenum, intestine, rectum, anus
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
Tonsillectomy - adverse effects
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Summary:There is some controversy about the prevalence of appendectomy and tonsillectomy among patients with Crohn's disease and a lower rate of appendectomy among patients with ulcerative colitis (UC). The objective of this study was to elucidate the role of appendectomy and tonsillectomy in Iranian patients with inflammatory bowel disease (IBD). Three hundred and eighty-two consecutive cases of UC and 46 cases of CD were included. Age and sex-matched controls were randomly selected. A total of 382 controls for UC and 184 controls for CD were enrolled. A standard record concerning smoking habit, history of appendectomy and tonsillectomy, OCP, and NSAID use was completed. Logistic regression analysis was used to evaluate potential confounding variables. Twelve patients (3.1%) with UC reported a previous history of appendectomy compared with 30 controls (7.9%) (OR=0.38, 95%CI=0.19-0.76, P
ISSN:0179-1958
1432-1262
DOI:10.1007/s00384-005-0760-3