The Mitral L Wave: A Marker of Advanced Diastolic Dysfunction in Patients With Atrial Fibrillation

Background The prominent mid-diastolic filling wave (mitral L wave) indicates advanced diastolic dysfunction in patients in sinus rhythm. The aim of the present study was to determine the clinical implications of the mitral L wave in patients with atrial fibrillation (AF). Methods and Results Ninety...

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Bibliographic Details
Published in:Circulation Journal 2007, Vol.71(8), pp.1244-1249
Main Authors: Nakai, Hiromi, Takeuchi, Masaaki, Nishikage, Tomoko, Nagakura, Toshiki, Otani, Shinichiro
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Atrial fibrillation
Atrial Fibrillation - physiopathology
Biomarkers
Blood Flow Velocity
Diastole
Diastolic function
Female
Heart Rate
Humans
Male
Middle Aged
Mitral L wave
Mitral Valve - physiopathology
Prevalence
Risk Factors
Sex Factors
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Summary:Background The prominent mid-diastolic filling wave (mitral L wave) indicates advanced diastolic dysfunction in patients in sinus rhythm. The aim of the present study was to determine the clinical implications of the mitral L wave in patients with atrial fibrillation (AF). Methods and Results Ninety-nine consecutive non-valvular chronic persistent AF patients were enrolled. The mitral L wave was defined as a distinct mid-diastolic flow velocity following the E wave with a peak velocity >20 cm/s. The prevalence of the L wave in AF patients (34/99, 34%) was significantly higher than that observed in patients in sinus rhythm during the same study period (23/946, 2.4%, p
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.71.1244