Increased serum levels of macrophage migration inhibitory factor in patients with Kawasaki disease

Objective: To determine whether serum levels of macrophage migration inhibitory factor (MIF) increase in patients with Kawasaki disease (KD) and also correlate with other inflammatory indices. Methods: Serum samples from 10 patients with KD, 15 normal healthy subjects, and seven febrile control subj...

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Bibliographic Details
Published in:Scandinavian journal of rheumatology 2007, Vol.36 (3), p.222-225
Main Authors: Lee, T. J., Chun, J. K., Yeon, S. I., Shin, J. S., Kim, D. S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biological and medical sciences
Child
Child, Preschool
Female
Humans
Interleukin-6 - blood
Macrophage Migration-Inhibitory Factors - blood
Male
Medical sciences
Middle Aged
Mucocutaneous Lymph Node Syndrome - blood
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
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Summary:Objective: To determine whether serum levels of macrophage migration inhibitory factor (MIF) increase in patients with Kawasaki disease (KD) and also correlate with other inflammatory indices. Methods: Serum samples from 10 patients with KD, 15 normal healthy subjects, and seven febrile control subjects were assayed for MIF by enzyme-linked immunosorbent assay (ELISA). Results: There was a significant increase in the serum levels of MIF in the acute stage of KD [113.06 (range 20.6-157.36) ng mL] compared with those in the subacute stage [28.11 (8.57-143.48) ng mL, p
ISSN:0300-9742
1502-7732
DOI:10.1080/03009740701218790