The effect of glutamine-enriched enteral nutrition on intestinal microflora in very low birth weight infants: A randomized controlled trial

Summary Background & aims In a previous study, we have found that glutamine supplementation decreased the infection rate in very low birth weight (VLBW) infants. In this study, we investigated whether this beneficial effect originated from increased number of bifidobacteria and lactobacilli in t...

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Bibliographic Details
Published in:Clinical nutrition (Edinburgh, Scotland) Scotland), 2007-08, Vol.26 (4), p.430-439
Main Authors: van den Berg, Anemone, van Elburg, Ruurd M, Westerbeek, Elisabeth A.M, van der Linde, Esmeralda G.M, Knol, J, Twisk, Jos W.R, Fetter, Willem P.F
Format: Article
Language:English
Subjects:
Bifidobacterium - drug effects
Bifidobacterium - growth & development
Biological and medical sciences
Colony Count, Microbial - methods
Diseases of mother, fetus and pregnancy
Double-Blind Method
Enteral nutrition
Enteral Nutrition - methods
Escherichia coli - drug effects
Escherichia coli - growth & development
Faecal flora
Feces - microbiology
Female
Fluorescent in situ hybridization
Gastroenterology and Hepatology
Glutamine
Glutamine - administration & dosage
Glutamine - pharmacology
Gynecology. Andrology. Obstetrics
Humans
In Situ Hybridization, Fluorescence - methods
Infant, Newborn
Infant, Very Low Birth Weight - growth & development
Intestines - microbiology
Lactobacillus - drug effects
Lactobacillus - growth & development
Male
Medical sciences
Metabolic diseases
Pregnancy. Fetus. Placenta
Randomized controlled trial
Time Factors
Treatment Outcome
Very low birth weight infant
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Summary:Summary Background & aims In a previous study, we have found that glutamine supplementation decreased the infection rate in very low birth weight (VLBW) infants. In this study, we investigated whether this beneficial effect originated from increased number of bifidobacteria and lactobacilli in the intestinal microflora of these infants. Methods In a randomized controlled trial, VLBW infants (gestational age
ISSN:0261-5614
1532-1983
DOI:10.1016/j.clnu.2007.03.002