Plasma Copper, Zinc, and Selenium Levels and Correlates with Metabolic Syndrome Components of Lebanese Adults

Zinc, copper, and selenium statuses were reported to be linked to the development of chronic diseases, especially coronary heart disease (CHD). Metabolic syndrome, a known CHD risk factor, was found to be highly prevalent in Lebanon. Nevertheless, no data are available on the statuses of plasma zinc...

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Bibliographic Details
Published in:Biological trace element research 2008-06, Vol.123 (1-3), p.58-65
Main Authors: Obeid, Omar, Elfakhani, Manal, Hlais, Sani, Iskandar, Michel, Batal, Malek, Mouneimne, Youssef, Adra, Nada, Hwalla, Nahla
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biochemistry
Biomedical and Life Sciences
Biotechnology
Cardiovascular diseases
Copper
Copper - blood
Female
Humans
Lebanon
Life Sciences
Male
Metabolic disorders
Metabolic Syndrome - blood
Metabolism
Middle Aged
Nutrition
Oncology
Plasma
Risk factors
Selenium
Selenium - blood
Spectrophotometry, Atomic
Studies
Zinc
Zinc - blood
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Summary:Zinc, copper, and selenium statuses were reported to be linked to the development of chronic diseases, especially coronary heart disease (CHD). Metabolic syndrome, a known CHD risk factor, was found to be highly prevalent in Lebanon. Nevertheless, no data are available on the statuses of plasma zinc, copper, and selenium, especially in terms of their relation to the components of the metabolic syndrome. A sample of 398 men and women aged 18–65 years was drawn from 23 health centers across Lebanon; anthropometric measurements and biochemical analyses of fasting plasma samples were performed. Subjects were found to have normal plasma statuses of copper and selenium but were at elevated risk of zinc deficiency. Plasma selenium levels correlated positively with all the components of the metabolic syndromes, while that of copper correlated only with total, high-density lipoprotein and low-density lipoprotein cholesterol. Plasma zinc did not correlate with any of the metabolic syndrome components.
ISSN:0163-4984
1559-0720
DOI:10.1007/s12011-008-8112-0