A novel integron in Salmonella enterica serovar Enteritidis, carrying the bla(DHA-1) gene and its regulator gene ampR, originated from Morganella morganii

The genetic organization of the gene coding for DHA-1 and the corresponding ampR gene was determined by PCR mapping. These genes have been mobilized from the Morganella morganii chromosome and inserted into a complex sulI-type integron, similar to In6 and In7. However, they are not themselves mobile...

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Bibliographic Details
Published in:Antimicrobial agents and chemotherapy 2000-01, Vol.44 (1), p.222-225
Main Authors: Verdet, C, Arlet, G, Barnaud, G, Lagrange, P H, Philippon, A
Format: Article
Language:English
Subjects:
Bacterial Proteins - genetics
Base Sequence
beta-Lactamases - genetics
Genes, Bacterial
Molecular Sequence Data
Polymerase Chain Reaction
Salmonella enterica - genetics
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Summary:The genetic organization of the gene coding for DHA-1 and the corresponding ampR gene was determined by PCR mapping. These genes have been mobilized from the Morganella morganii chromosome and inserted into a complex sulI-type integron, similar to In6 and In7. However, they are not themselves mobile cassettes. This integron probably includes a specific site for recombination allowing the mobilization of diverse resistance genes, as observed for bla(CMY-1) and bla(MOX-1).
ISSN:0066-4804
DOI:10.1128/AAC.44.1.222-225.2000