Resistance gene capture

Integrons are the primary mechanism for antibiotic-resistance gene capture and dissemination among Gram-negative bacteria. The recent finding of super-integron structures in the genomes of several bacterial species has expanded their role in genome evolution and suggests that they are the source of...

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Bibliographic Details
Published in:Current Opinion in Microbiology 1999-10, Vol.2 (5), p.483-488
Main Authors: Rowe-Magnus, Dean A, Mazel, Didier
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Antibiotic resistance
Bacteria - drug effects
Bacteria - genetics
DNA Transposable Elements
Drug Resistance, Microbial - genetics
Gene capture
Genes, Bacterial
Humans
integrons
Multi-resistant integrons
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Summary:Integrons are the primary mechanism for antibiotic-resistance gene capture and dissemination among Gram-negative bacteria. The recent finding of super-integron structures in the genomes of several bacterial species has expanded their role in genome evolution and suggests that they are the source of mobile multi-resistant integrons.
ISSN:1369-5274
1879-0364
DOI:10.1016/S1369-5274(99)00004-1