Case of retinochoroiditis associated with porcine ascarids diagnosed by antibodies in subretinal fluid

Purpose To determine the cause of retinochorioditis in a patient with a granulomatous retinal exudate and an exudative retinal detachment. Case A 45-year-old man presented at another hospital with increased visual disturbances of the left eye. He was diagnosed with uveitis, and treated with topical...

Full description

Saved in:
Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2008-07, Vol.246 (7), p.1065-1067
Main Authors: Matsuyama, Kayako, Ogata, Nahoko, Takahashi, Kanji, Matsumura, Miyo, Nishimura, Tetsuya
Format: Article
Language:English
Subjects:
Albendazole - therapeutic use
Animals
Antibodies, Helminth - blood
Antiprotozoal Agents - therapeutic use
Ascaridia - immunology
Ascaridia - isolation & purification
Ascaridiasis - drug therapy
Ascaridiasis - immunology
Ascaridiasis - parasitology
Body Fluids - immunology
Case Report
Chorioretinitis - drug therapy
Chorioretinitis - immunology
Chorioretinitis - parasitology
Drug Therapy, Combination
Enzyme-Linked Immunosorbent Assay
Exudates and Transudates - immunology
Eye Infections, Parasitic - drug therapy
Eye Infections, Parasitic - immunology
Eye Infections, Parasitic - parasitology
Glucocorticoids - therapeutic use
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Ophthalmology
Prednisolone - therapeutic use
Swine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To determine the cause of retinochorioditis in a patient with a granulomatous retinal exudate and an exudative retinal detachment. Case A 45-year-old man presented at another hospital with increased visual disturbances of the left eye. He was diagnosed with uveitis, and treated with topical steroids for 1 month. However, the uveitis worsened, and he was referred to our hospital. Ophthalmoscopy showed a yellowish-white granulomatous exudate, and an exudative retinal detachment in the lower peripheral retina. The retinal detachment worsened and affected the macula. Pars plana vitrectomy was performed, and the retina was reattached. During the surgery, ocular samples were collected for further examinations. The titers of antibodies against 12 kinds of ascaridis were examined, and elevated titers of specific antibodies against porcine ascarids were detected in the subretinal fluid, but not in the aqueous humor, vitreous, or serum. Conclusions Vitrectomy with the collection of ocular samples, especially subretinal fluid, was a key procedure in the diagnosis and treatment of retinochoroiditis associated with the porcine ascarids.
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-008-0790-y