Aqueous two-phase : the system of choice for extractive fermentation

Extractive fermentation in aqueous two-phase systems is a meaningful approach to overcome low product yield in a conventional fermentation process, and by proper design of the two-phase system it is possible to obtain the product in a cell-free stream. The characteristics of an aqueous two-phase sys...

Full description

Saved in:
Bibliographic Details
Published in:Applied microbiology and biotechnology 2000-10, Vol.54 (4), p.476-486
Main Authors: SINHA, J, DEY, P. K, PANDA, T
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - biosynthesis
Biological and medical sciences
Biotechnology
Cell Division
Culture Techniques
Enzymes - biosynthesis
Fermentation
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Microbial engineering. Fermentation and microbial culture technology
Physicochemical properties
Polymers
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Extractive fermentation in aqueous two-phase systems is a meaningful approach to overcome low product yield in a conventional fermentation process, and by proper design of the two-phase system it is possible to obtain the product in a cell-free stream. The characteristics of an aqueous two-phase system, various polymers used for forming an aqueous two-phase system, the physicochemical parameters of the aqueous two-phase system, partitioning of biomolecules and cell mass and the effect of individual phase forming polymers on cell growth and product formation are reviewed in this article. The various extractive fermentation processes are also summarised here. At the end, the economic viability and scope of aqueous two-phase fermentation are briefly discussed in relation to the wider application of this topic.
ISSN:0175-7598
1432-0614
DOI:10.1007/s002530000342