Novel structures of plant lectins and their complexes with carbohydrates

Several novel structures of legume lectins have led to a thorough understanding of monosaccharide and oligosaccharide specificity, to the determination of novel and surprising quaternary structures and, most importantly, to the structural identification of the binding site for adenine and plant horm...

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Bibliographic Details
Published in:Current Opinion in Structural Biology 1999-10, Vol.9 (5), p.572-577
Main Authors: Bouckaert, Julie, Hamelryck, Thomas, Wyns, Lode, Loris, Remy
Format: Article
Language:English
Subjects:
Binding Sites
Carbohydrate recognition
Carbohydrates - chemistry
Dimerization
Lectin
Lectins - chemistry
Macromolecular Substances
Models, Molecular
Plant Growth Regulators - chemistry
Plant Lectins
Plants
Protein Conformation
Protein Structure, Quaternary
Protein Structure, Secondary
Protein–carbohydrate interaction
Quaternary structure
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Summary:Several novel structures of legume lectins have led to a thorough understanding of monosaccharide and oligosaccharide specificity, to the determination of novel and surprising quaternary structures and, most importantly, to the structural identification of the binding site for adenine and plant hormones. This deepening of our understanding of the structure/function relationships among the legume lectins is paralleled by advances in two other plant lectin families — the monocot lectins and the jacalin family. As the number of available crystal structures increases, more parallels between plant and animal lectins become apparent.
ISSN:0959-440X
1879-033X
DOI:10.1016/S0959-440X(99)00007-X