Interobserver and intraobserver reproducibility of peripheral blood and oxygen pressure measurements in the assessment of lower extremity arterial disease

• Published in: Journal of vascular surgery 2001-05, Vol.33 (5), p.1033-1040
• Main Authors: de Graaff, Jurgen C., Ubbink, Dirk Th, Legemate, Dink A., de Haan, Rob J., Jacobs, Michael J.H.M.
• Format: Article
• Language: English
• Subjects: Aged; Ankle - blood supply; Biological and medical sciences; Blood and lymphatic vessels; Blood Gas Monitoring, Transcutaneous; Blood Pressure Determination - methods; Cardiology. Vascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Hallux - blood supply; Humans; Intermittent Claudication - blood; Intermittent Claudication - physiopathology; Ischemia - blood; Ischemia - physiopathology; Leg - blood supply; Male; Medical sciences; Observer Variation; Photoplethysmography; Reproducibility of Results; Toes - blood supply
• ISSN: 0741-5214; 1097-6809
• DOI: 10.1067/mva.2001.108011

Introduction: Peripheral blood pressure measurements play a prominent role in the diagnosis and follow-up of patients with peripheral vascular diseases. Toe pressure of the hallux (TP1) and second toe (TP2) and transcutaneous oxygen pressure (TCPO2) measurements are becoming more important. The ankle/brachial pressure index (ABPI) is known to be a reliable parameter, but the toe pressure and TCPO2 are evaluated less thoroughly. Therefore, we evaluated the reproducibility of TP1, TP2, TCPO2, ABPI, ankle pressure (AP), and brachial pressure (BP). Patients and Methods: In 54 patients with various stages of peripheral vascular disease, the intraobserver and interobserver reproducibility of BP, AP, ABPI, TP1, TP2, and TCPO2 was investigated by calculating the repeatability coefficient (RC) and the intraclass correlation coefficient (ICC) and by using Bland-Altman plots. Results: The intraobserver and interobserver reproducibility at 1 day and after 1 week of BP, AP, ABPI, and TP1 was substantial and comparable (ICC range, 0.80-0.99), except for the BP after 1 week. The TP2 and TCPO2 were less reproducible (ICC range, 0.62-0.98). The interobserver RC of BP was 31 mm Hg; of AP, 44 mm Hg; of ABPI, 27%; of TP1, 41 mm Hg; of TP2, 67 mm Hg; and of TCPO2; 30 mm Hg. The difference plot showed that the observer variability was equally distributed across the range of pressure in all measurements. Conclusion: The BP, AP, ABPI, and TP1 have a substantial intraobserver and interobserver reproducibility, whereas TP2 and TCPO2 show worse reproducibility. Especially when low values (or values around a cutoff value) are measured, the RC should be taken into account, and repetition of the measurement is advocated. (J Vasc Surg 2001;33:1033-40.)