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Risk Factors for Community-Acquired Pneumonia among Persons Infected with Human Immunodeficiency Virus

Two hundred eleven adults with human immunodeficiency virus (HIV) infection hospitalized for community-acquired pneumonia, including Pneumocystis carinii pneumonia (PCP; patients), and 192 matched HIV-infected hospitalized patients without pneumonia (controls) were interviewed to determine risk fact...

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Published in:The Journal of infectious diseases 2000-01, Vol.181 (1), p.158-164
Main Authors: Navin, Thomas R., Rimland, David, Lennox, Jeffrey L., Jernigan, John, Cetron, Marty, Hightower, Allen, Roberts, Jacqueline M., Kaplan, Jonathan E.
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container_start_page 158
container_title The Journal of infectious diseases
container_volume 181
creator Navin, Thomas R.
Rimland, David
Lennox, Jeffrey L.
Jernigan, John
Cetron, Marty
Hightower, Allen
Roberts, Jacqueline M.
Kaplan, Jonathan E.
description Two hundred eleven adults with human immunodeficiency virus (HIV) infection hospitalized for community-acquired pneumonia, including Pneumocystis carinii pneumonia (PCP; patients), and 192 matched HIV-infected hospitalized patients without pneumonia (controls) were interviewed to determine risk factors for pneumonia. Multivariate logistic regression showed that patients were less likely than controls to have used trimethoprim-sulfamethox-azole (TMP-SMZ) prophylaxis (odds ratio [OR], 0.22; 95% confidence interval [CI], 0.12–0.41) and more likely to have been hospitalized previously with pneumonia (OR, 6.25; CI, 3.40–11.5). Patients were also more likely than controls to have gardened (OR, 2.24; CI, 1.00–5.02) and to have camped or hiked (OR, 4.95; CI, 1.31–18.7), but stratified analysis by etiologic agent showed this association only for PCP. These findings reconfirm the efficacy of TMP-SMZ in preventing community-acquired pneumonia. In addition, hospitalization for pneumonia might represent a missed opportunity to encourage HIV-infected patients to enter into regular medical care and to adhere to prescribed antiretroviral and prophylaxis medications.
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source JSTOR Archival Journals and Primary Sources Collection; Oxford Journals Online
subjects Adult
AIDS
AIDS/HIV
Bacterial pneumonia
Biological and medical sciences
Community-Acquired Infections - etiology
Community-Acquired Infections - prevention & control
Female
HIV
HIV Infections - complications
Human immunodeficiency virus
Human viral diseases
Humans
Infections
Infectious diseases
Logistic Models
Major Articles
Male
Medical sciences
Men
Middle Aged
Operating rooms
Pneumocystis carinii
Pneumocystis pneumonia
Pneumonia
Pneumonia - etiology
Pneumonia - prevention & control
Pneumonia, Pneumocystis - etiology
Pneumonia, Pneumocystis - prevention & control
Predisposing factors
Risk Factors
Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral pneumonia
title Risk Factors for Community-Acquired Pneumonia among Persons Infected with Human Immunodeficiency Virus
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