Kidney damage during organ retrieval: data from UK National Transplant Database. Kidney Advisory Group

Kidney damage at organ retrieval is believed to be an increasing problem that is under reported. We aimed to identify the true rate of such damage and assess the effects on transplant survival. Data from the UK National Transplant Database were analysed on all cadaveric kidneys donated over a 5-year...

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Bibliographic Details
Published in:The Lancet (British edition) 1999-10, Vol.354 (9185), p.1143-1146
Main Authors: Wigmore, S J, Seeney, F M, Pleass, H C, Praseedom, R K, Forsythe, J L
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Cadaver
Child
Child, Preschool
Databases, Factual
Humans
Infant
Infant, Newborn
Kidney - injuries
Kidney Transplantation - statistics & numerical data
Middle Aged
Multivariate Analysis
Proportional Hazards Models
Tissue Survival
United Kingdom
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Summary:Kidney damage at organ retrieval is believed to be an increasing problem that is under reported. We aimed to identify the true rate of such damage and assess the effects on transplant survival. Data from the UK National Transplant Database were analysed on all cadaveric kidneys donated over a 5-year period in the UK. Records indicated whether kidneys had been retrieved by a liver or renal surgical team and whether damage was noted at the time of retrieval or at the transplant procedure. Multivariate Cox's regression models were fitted to 1-year and 3-year transplant-survival data in those kidneys that were transplanted between 1992 and 1994. Of 9014 kidneys retrieved, 96 could not be transplanted because of damage sustained at retrieval. Damage was reported in 1726 (19%) kidneys although by both donor and recipient centres in only 270 (3%). 1070 (62%) of the damaged organs were from donors aged 40 years or older. Reported kidney damage was more likely for retrievals of kidney only by a renal team (503 [26%]) than for multiorgan retrieval (454 [21%]), the proportion was lower when a liver team retrieved both liver and kidneys (415 [17%]). 794 (14%) kidneys retrieved and retained locally were reported as damaged, compared with 932 (29%) kidneys which had been exported. Donors' age had a significant effect on both 1-year and 3-year transplant survival (p
ISSN:0140-6736