Cognitive function in euthymic Bipolar I Disorder

Recent reports have suggested the presence of persistent cognitive impairments in patients diagnosed with Bipolar Disorder even after prolonged euthymic phases. In this work, various domains of cognitive function were examined in asymptomatic patients diagnosed with Bipolar I Disorder (BDI) in compa...

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Bibliographic Details
Published in:Psychiatry research 2001-05, Vol.102 (1), p.9-20
Main Authors: Zubieta, Jon-Kar, Huguelet, Philippe, O'Neil, Renee Lajiness, Giordani, Bruno J.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Age Distribution
Biological and medical sciences
Bipolar disorder
Bipolar Disorder - psychology
Bipolar disorders
Cognition Disorders - diagnosis
Cognition Disorders - epidemiology
Cognition Disorders - etiology
Course of illness
Executive functions
Female
Humans
Learning
Male
Medical sciences
Memory
Mood disorders
Neuropsychological Tests
Psychology. Psychoanalysis. Psychiatry
Psychomotor function
Psychopathology. Psychiatry
Severity of Illness Index
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Summary:Recent reports have suggested the presence of persistent cognitive impairments in patients diagnosed with Bipolar Disorder even after prolonged euthymic phases. In this work, various domains of cognitive function were examined in asymptomatic patients diagnosed with Bipolar I Disorder (BDI) in comparison with healthy subjects. Fifteen otherwise healthy BDI patients with a prior history of psychosis during mania completed a neuropsychological testing battery after a prolonged asymptomatic remission. Their scores were compared to those of individually matched healthy subjects with unpaired two-tailed t-tests at P
ISSN:0165-1781
1872-7123
DOI:10.1016/S0165-1781(01)00242-6