Prognosis of Late-Onset Depression in the Elderly: A Study From India

Objective: To study the 12-month outcome of late-onset depression in elderly persons and the predictive factors affecting its outcome. Method: This is a prospective study of 50 patients who had their first major depressive episode (according to DSM-III-R) in old age (60 years and above) and attended...

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Bibliographic Details
Published in:International psychogeriatrics 2001-03, Vol.13 (1), p.51-61
Main Authors: Jhingan, Harsh Prem, Sagar, Rajesh, Pandey, Ravindra Mohan
Format: Article
Language:English
Subjects:
Age
Age Factors
Aged
Biological and medical sciences
Clinical outcomes
Dementia
Depression - diagnosis
Depression - therapy
Depressive Disorder, Major - diagnosis
Depressive Disorder, Major - epidemiology
Depressive Disorder, Major - psychology
Depressive Disorder, Major - therapy
Family Characteristics
Female
Follow-Up Studies
Geriatrics
Humans
Hypertension
Illnesses
India - epidemiology
Logistic Models
Male
Medical prognosis
Medical sciences
Mental depression
Middle Aged
Mortality
Odds Ratio
Older people
Outcome Assessment (Health Care)
Outpatients - statistics & numerical data
Patients
Prognosis
Prospective Studies
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Remission Induction
Secondary Prevention
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Summary:Objective: To study the 12-month outcome of late-onset depression in elderly persons and the predictive factors affecting its outcome. Method: This is a prospective study of 50 patients who had their first major depressive episode (according to DSM-III-R) in old age (60 years and above) and attended the psychiatry services of a tertiary care hospital in India. These patients were assessed at baseline and after 12 months for clinical outcome. Stepwise logistic regression was applied to determine predictive factors for the clinical outcome. Results: Twenty-eight percent of the patients had recovered, 30% had partially recovered, 23% had relapsed, 6% had been continuously ill, 11% had died, and 6% had comorbid dementia. Factors predicting a good outcome (full recovery and continuously well for 1 year) were shorter duration of episode (adjusted odds ratio [OR] = 19.15, 95% confidence interval [CI] 2.12-172.82) and living in joint family system (adjusted OR = 4.88, 95% CI 0.80-29.74). Conclusion: Overall, the 12-month outcome was poor in elderly individuals with late-onset depression.
ISSN:1041-6102
1741-203X
DOI:10.1017/S1041610201007451