The distribution, metabolism and function of creatine in the male mammalian reproductive tract: a review

Creatine is widely distributed throughout the male reproductive system in several mammalian species, and proteins involved in its metabolism and transport have been reported in a number of cell and tissue types. Creatine is synthesized within some organs, incorporating nitrogen from amino acid metab...

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Bibliographic Details
Published in:International journal of andrology 2000-02, Vol.23 (1), p.4-12
Main Author: Moore, N. P.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
creatine
Creatine - metabolism
energy metabolism
Fundamental and applied biological sciences. Psychology
Genitalia, Male - metabolism
Humans
Intermediate and energetic metabolism
Male
male reproductive tract
Metabolisms and neurohumoral controls
Species Specificity
sperm
testis
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:Creatine is widely distributed throughout the male reproductive system in several mammalian species, and proteins involved in its metabolism and transport have been reported in a number of cell and tissue types. Creatine is synthesized within some organs, incorporating nitrogen from amino acid metabolism. Although creatine metabolism is obligatory for the motility of sea urchin spermatozoa, this does not appear to be the case for mammals. The possible functions of creatine within the reproductive tract are discussed.
ISSN:0105-6263
1365-2605
DOI:10.1046/j.1365-2605.2000.00197.x