Relationships among bone mineral densities, static alignment and dynamic load in patients with medial compartment knee osteoarthritis

Objective. To investigate the relationships among bone mineral density (BMD), static alignment and the adduction moment of the knee in patients with tibiofemoral osteoarthritis (OA). Methods. Sixty‐nine patients with medial compartment knee OA underwent radiographic evaluation, gait analysis and BMD...

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Bibliographic Details
Published in:Rheumatology (Oxford, England) England), 2001-05, Vol.40 (5), p.499-505
Main Authors: Wada, M., Maezawa, Y., Baba, H., Shimada, S., Sasaki, S., Nose, Y.
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Aged
Aged, 80 and over
Alignment
Biological and medical sciences
Bone Density - physiology
Bone mineral density
Diseases of the osteoarticular system
Female
Humans
Knee osteoarthritis
Lumbar Vertebrae - diagnostic imaging
Lumbar Vertebrae - metabolism
Male
Mechanical load
Medical sciences
Middle Aged
Osteoarthritis, Knee - diagnostic imaging
Osteoarthritis, Knee - metabolism
Osteoarthritis, Knee - physiopathology
Osteoporosis. Osteomalacia. Paget disease
Posture - physiology
Range of Motion, Articular - physiology
Stress, Mechanical
Tibia - diagnostic imaging
Tibia - metabolism
Weight-Bearing - physiology
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Summary:Objective. To investigate the relationships among bone mineral density (BMD), static alignment and the adduction moment of the knee in patients with tibiofemoral osteoarthritis (OA). Methods. Sixty‐nine patients with medial compartment knee OA underwent radiographic evaluation, gait analysis and BMD measurements at the proximal tibia and lumbar spine. Results. The bone mineral distribution of the medial to lateral part of the proximal tibia correlated significantly with the peak knee adduction moment and the mechanical axis. Furthermore, the adduction moment correlated significantly with the mechanical axis. However, the BMD of the lumbar spine and the bone mineral distribution of the posterior to anterior part of the proximal tibia did not correlate with any other measurement. Conclusions. Our results suggest that the bone mineral distribution of the proximal tibia is directly affected but lumbar BMD is not influenced by the local mechanical stress around the knee with medial compartment OA.
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/40.5.499