Diagnostic Intraocular Fine-Needle Aspiration Biopsy-An Experience in Three Cases of Retinoblastoma

Ophthalmoscopically guided intraocular fine‐needle aspiration biopsy (FNAB) under general anesthesia was performed in three suspected cases of retinoblastoma (Rb). The first case presented with uveitis and the second with unusual radiological features. The third case had classical clinical features...

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Bibliographic Details
Published in:Diagnostic cytopathology 1999-11, Vol.21 (5), p.331-334
Main Authors: Sen, Seema, Singha, Ujwala, Kumar, Harsh, Ghose, Supriyo, Sarkar, Tarun, Bajaj, Mandeep S.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle - methods
Child
Child, Preschool
cytology
Female
FNAB
Humans
intraocular tumor
Male
Medical sciences
Ophthalmology
Retinal Neoplasms - diagnostic imaging
Retinal Neoplasms - pathology
retinoblastoma
Retinoblastoma - diagnostic imaging
Retinoblastoma - pathology
Tropical medicine
Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus
Ultrasonography
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Summary:Ophthalmoscopically guided intraocular fine‐needle aspiration biopsy (FNAB) under general anesthesia was performed in three suspected cases of retinoblastoma (Rb). The first case presented with uveitis and the second with unusual radiological features. The third case had classical clinical features of bilateral Rb but the parents refused enucleation. After a cytologic diagnosis of retinoblastoma, two cases were subjected to enucleation and a histologic confirmation was obtained. The present article discusses the technique of guided intraocular FNAB and its limitations as well as utility in the preoperative diagnosis of retinoblastoma (Rb). The authors are of the opinion that FNAB should be considered a viable diagnostic option in selected cases of leucocoria when conventional investigative modalities prove inconclusive or for tissue diagnosis when a patient of suspected Rb refuses enucleation. Diagn. Cytopathol. 1999;21:331–334. © 1999 Wiley‐Liss, Inc.
ISSN:8755-1039
1097-0339
DOI:10.1002/(SICI)1097-0339(199911)21:5<331::AID-DC7>3.0.CO;2-K