A trial of etomidate for rapid sequence intubation in the emergency department

A number of pharmacologic agents have been used for induction during rapid sequence intubation (RSI). Some of these agents may have adverse effects that can limit their use in certain clinical settings. This study was undertaken to determine the safety and utility of etomidate in patients with a ran...

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Bibliographic Details
Published in:The Journal of emergency medicine 2000, Vol.18 (1), p.13-16
Main Authors: Smith, Daniel C, Bergen, Joseph M, Smithline, Howard, Kirschner, Ronald
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
airway
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
Emergency Treatment
etomidate
Etomidate - pharmacology
Female
Hemodynamics - drug effects
Humans
Hypnotics and Sedatives - pharmacology
induction agents
intubation
Intubation, Intratracheal - methods
Male
Medical sciences
Middle Aged
Neuropharmacology
Pharmacology. Drug treatments
Prospective Studies
rapid sequence intubation
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Summary:A number of pharmacologic agents have been used for induction during rapid sequence intubation (RSI). Some of these agents may have adverse effects that can limit their use in certain clinical settings. This study was undertaken to determine the safety and utility of etomidate in patients with a range of underlying clinical conditions. Thirty-four patients underwent RSI in the emergency department (ED). Hemodynamic measurements and clinical assessments were recorded before and after intubation. The results suggest that etomidate is a safe and effective agent for use in a range of patients undergoing RSI in the ED.
ISSN:0736-4679
2352-5029
DOI:10.1016/S0736-4679(99)00154-7