Microwave spectroscopy of myocardial ischemia and infarction. 2. Biophysical reconstruction

The proposed dielectrical relaxation model of the myocardium in the microwave spectrum has been verified both on test solutions and on normal canine myocardium. Furthermore, the model was utilized to reconstruct the changes in tissue properties (including myocardial bulk resistance and water content...

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Bibliographic Details
Published in:Annals of biomedical engineering 2000-01, Vol.28 (1), p.55-60
Main Authors: Semenov, S Y, Svenson, R H, Bulyshev, A E, Souvorov, A E, Nazarov, A G, Sizov, Y E, Posukh, V G, Pavlovsky, A, Tatsis, G P
Format: Article
Language:English
Subjects:
Acute Disease
Algorithms
Animals
Biomedical Engineering
Biophysical Phenomena
Biophysics
Body Water - metabolism
Cardiovascular system
Chronic Disease
Dielectric relaxation
Dogs
Electrophysiology
Engineering societies
Female
Infarction
Ischemia
Male
Mathematical models
Microwave spectroscopy
Microwaves
Models, Cardiovascular
Moisture content
Myocardial Infarction - pathology
Myocardial Infarction - physiopathology
Myocardial ischemia
Myocardial Ischemia - pathology
Myocardial Ischemia - physiopathology
Myocardium
Probes
Spectroscopy
Tissue
Tomography - methods
Water content
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Summary:The proposed dielectrical relaxation model of the myocardium in the microwave spectrum has been verified both on test solutions and on normal canine myocardium. Furthermore, the model was utilized to reconstruct the changes in tissue properties (including myocardial bulk resistance and water content) following myocardial acute ischemia and chronic infarction. It was shown that the reconstructed myocardial resistance and water content correlate dynamically with the process of the development of acute myocardial ischemic injury. In chronic cases the reconstructed resistance and water content of infarcted myocardium are significantly different from that of normal myocardium: the resistance is lower and water content is higher than in normal myocardium.
ISSN:0090-6964
1573-9686
DOI:10.1114/1.254