B cell leukaemia/lymphoma‐2 protein concentrations during normal pregnancy

We evaluated bcl‐2 protein levels in whole blood, and intraerythrocytic products of lipoperoxidation, in 65 healthy pregnant primiparous women at the end of the first, second and third trimesters of pregnancy. During pregnancy we found a progressive increase in concentrations of bcl‐2 and intraeryth...

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Bibliographic Details
Published in:BJOG : an international journal of obstetrics and gynaecology 2000-01, Vol.107 (1), p.133-134
Main Authors: Buemi, M., Allegra, A., Corica, F., D'Anna, R., Ruello, A., Jasonni, V. M.
Format: Article
Language:English
Subjects:
Female
Humans
Lipid Peroxides - metabolism
Pregnancy - metabolism
Proto-Oncogene Proteins c-bcl-2 - metabolism
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Summary:We evaluated bcl‐2 protein levels in whole blood, and intraerythrocytic products of lipoperoxidation, in 65 healthy pregnant primiparous women at the end of the first, second and third trimesters of pregnancy. During pregnancy we found a progressive increase in concentrations of bcl‐2 and intraerythrocytic products of lipoperoxidation. Moreover, a positive correlation was found between bcl‐2 concentrations and lipoperoxidation products, and between bcl‐2 protein, E2 and progesterone. The results show that modifications occurring during pregnancy are accompanied by variations of bcl‐2 protein.
ISSN:1470-0328
1471-0528
DOI:10.1111/j.1471-0528.2000.tb11591.x