Melanoma lymphoscintigraphy and lymphatic mapping

Lymphoscintigraphy in melanoma has proven to be a reliable method to identify regional lymph nodes at risk for metastases. The first lymph node to drain a cutaneous lesion, the sentinel lymph node (SLN), is predictive of the metastatic status of the regional lymph node group. Lymphatic mapping allow...

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Bibliographic Details
Published in:Seminars in nuclear medicine 2000, Vol.30 (1), p.49-55
Main Authors: Berman, Claudia G., Choi, Junsung, Hersh, Marla R., Clark, Robert A.
Format: Article
Language:English
Subjects:
Humans
Lymph Nodes - diagnostic imaging
Lymphatic Metastasis - diagnostic imaging
Melanoma - diagnostic imaging
Melanoma - pathology
Neoplasm Staging
Radioimmunodetection
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Summary:Lymphoscintigraphy in melanoma has proven to be a reliable method to identify regional lymph nodes at risk for metastases. The first lymph node to drain a cutaneous lesion, the sentinel lymph node (SLN), is predictive of the metastatic status of the regional lymph node group. Lymphatic mapping allows for the identification of the SLN and for selective lymph node sampling. Selective lymph node sampling is less invasive and because only a small quantity of high-risk tissue is submitted for pathological examination, it allows for a more complete and comprehensive pathological examination, which identifies melanoma with up to 100 times the sensitivity of conventional examinations.
ISSN:0001-2998
1558-4623
DOI:10.1016/S0001-2998(00)80061-6