HLA class II antigens in South African Blacks with type I diabetes

: Type 1 diabetes mellitus is poorly characterised in many African communities, including South Africa, where little is known of the disease epidemiology. This study aimed to identify the HLA class II alleles associated with type 1 diabetes in a group of Zulu subjects in Durban, KwaZulu‐Natal by PCR...

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Bibliographic Details
Published in:Tissue antigens 2001-04, Vol.57 (4), p.348-352
Main Authors: Pirie, F.J., Hammond, M.G., Motala, A.A., Omar, M.A.K.
Format: Article
Language:English
Subjects:
Adult
African Continental Ancestry Group - genetics
Alleles
Diabetes Mellitus, Type 1 - epidemiology
Diabetes Mellitus, Type 1 - genetics
Diabetes Mellitus, Type 1 - immunology
Gene Frequency - immunology
Genetic Predisposition to Disease
Haplotypes
histocompatibility locus HLA
HLA class II alleles
HLA-D Antigens - genetics
Humans
Incidence
South Africa - epidemiology
South African Blacks
type 1 diabetes mellitus
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Summary:: Type 1 diabetes mellitus is poorly characterised in many African communities, including South Africa, where little is known of the disease epidemiology. This study aimed to identify the HLA class II alleles associated with type 1 diabetes in a group of Zulu subjects in Durban, KwaZulu‐Natal by PCR‐SSP. The HLA alleles associated with type 1 diabetes included HLA‐DQB*0302 (P
ISSN:0001-2815
1399-0039
DOI:10.1034/j.1399-0039.2001.057004348.x