Use of meropenem 3 g once daily for outpatient treatment of infective exacerbations of bronchiectasis

Meropenem administered as a single iv 3 g dose once every 24 h was used to treat nine ambulatory patients with infective exacerbations of bronchiectasis. Serum meropenem concentrations were measured before dosing and at 30 min after each 30 min infusion. Mean pre-dose concentrations were

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 2000-02, Vol.45 (2), p.247-250
Main Authors: DARLEY, E. S. R, BOWKER, K. E, LOVERING, A. M, HARVEY, J. E, MACGOWAN, A. P
Format: Article
Language:English
Subjects:
Aged
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Bronchiectasis - complications
Bronchiectasis - microbiology
Female
Haemophilus Infections - drug therapy
Haemophilus Infections - microbiology
Haemophilus influenzae
Half-Life
Humans
Male
Medical sciences
Meropenem
Middle Aged
Pharmacology. Drug treatments
Pneumococcal Infections - drug therapy
Pneumococcal Infections - microbiology
Pseudomonas Infections - drug therapy
Pseudomonas Infections - microbiology
Respiratory Tract Infections - drug therapy
Respiratory Tract Infections - etiology
Respiratory Tract Infections - microbiology
Thienamycins - therapeutic use
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Description
Summary:Meropenem administered as a single iv 3 g dose once every 24 h was used to treat nine ambulatory patients with infective exacerbations of bronchiectasis. Serum meropenem concentrations were measured before dosing and at 30 min after each 30 min infusion. Mean pre-dose concentrations were
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/45.2.247