Haemoconcentration by gelatin‐induced acceleration of erythrocyte sedimentation rate

• Published in: Anaesthesia 2000-03, Vol.55 (3), p.217-220
• Main Authors: Sümpelmann, R., Günther, A., Zander, R.
• Format: Article
• Language: English
• Subjects: Albumins - pharmacology; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Sedimentation - drug effects; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Excipients - pharmacology; Fluids, intravenous; albumin, hydroxyethyl starch, modified gelatin, normal saline; Gelatin - pharmacology; Humans; Hydroxyethyl Starch Derivatives - pharmacology; Investigations, haematological; erythrocyte sedimentation rate; Medical sciences; Osmolar Concentration; Plasma Substitutes - pharmacology; Sodium Chloride - pharmacology; Transfusions. Complications. Transfusion reactions. Cell and gene therapy
• ISSN: 0003-2409; 1365-2044
• DOI: 10.1046/j.1365-2044.2000.01211.x

Erythrocyte sedimentation rates from 40 suspensions of packed red blood cells in modified fluid gelatin, 4% albumin solution, 6% hydroxyethyl starch and normal saline were measured at room temperature using Westergren's method. The erythrocyte sedimentation rate was extremely high in gelatin and this increase was significant after 10–60 min when compared with the other fluids. Erythrocyte sedimentation rates in albumin, hydroxyethyl starch and normal saline were low and there were no differences between these fluids [erythrocyte sedimentation after 60 min, median (interquartile range): gelatin 128 (111.2–130.0) mm, albumin 2 (1.5–2.0) mm, hydroxyethyl starch 1.5 (1.0–1.6) mm, normal saline 2 (1.9–2.5) mm, p