Myoepithelioma presenting as a midline cystic tongue lesion: Cytology, histology, ancillary studies, and differential diagnosis

Salivary gland myoepithelioma (ME) is a neoplasm derived from myoepithelial cells that lacks the ductal and broad mesenchymal differentiation seen in the vast majority of mixed tumors. This report describes the cytologic findings of a cystic ME presenting in the midline of the dorsal tongue, a site...

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Bibliographic Details
Published in:Diagnostic cytopathology 2001-06, Vol.24 (6), p.403-407
Main Authors: De Las Casas, Luis E., Hoerl, H.D., Oberley, T.D., Hafez, G.R., Sempf, J.M., Shalkham, J.E., Kurtycz, D.F.I.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Biopsy, Needle
Diagnosis, Differential
fine-needle aspiration
Humans
Male
Medical sciences
myoepithelioma
Myoepithelioma - diagnosis
Myoepithelioma - pathology
Myoepithelioma - surgery
Otorhinolaryngology. Stomatology
salivary gland neoplasm
tongue
Tongue - cytology
Tongue - surgery
Tongue Neoplasms - diagnosis
Tongue Neoplasms - pathology
Tongue Neoplasms - surgery
Treatment Outcome
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Summary:Salivary gland myoepithelioma (ME) is a neoplasm derived from myoepithelial cells that lacks the ductal and broad mesenchymal differentiation seen in the vast majority of mixed tumors. This report describes the cytologic findings of a cystic ME presenting in the midline of the dorsal tongue, a site where no salivary glands are generally present. The tumor was well circumscribed and composed of sheets of monotonous epithelioid cells without ductal cells. The cells were positive for S‐100 protein and ultrastructurally had features of myoepithelial cells. The fine needle aspiration (FNA) biopsy findings, differential diagnosis, histology, immunohistochemistry, and electron microscopic features of this interesting and uncommon neoplasm are presented. To the best of our knowledge, there have been no cytologic reports of ME of the tongue. Diagn. Cytopathol. 24:403–407, 2001. © 2001 Wiley‐Liss, Inc.
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.1089