Anxiety and pain suppress the natural killer cell activity in oral surgery outpatients

Objective. Psychological stress has an influence on natural killer cell (NK) activity, which plays a central role in protection against microbial infection and cancer. Anxiety concerning cancer is a typical type of psychological stress observed in patients and is associated with various diseases. In...

Full description

Saved in:
Bibliographic Details
Published in:Oral surgery, oral medicine, oral pathology, oral radiology and endodontics oral medicine, oral pathology, oral radiology and endodontics, 2001-06, Vol.91 (6), p.654-658
Main Authors: Koga, Chihiro, Itoh, Kyogo, Aoki, Masatora, Suefuji, Yuuichi, Yoshida, Minako, Asosina, Sumiko, Esaki, Kazuhisa, Kameyama, Tadamitsu
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Alcohol Drinking - psychology
Ambulatory Surgical Procedures
Analysis of Variance
Anxiety - immunology
Anxiety - psychology
Biological and medical sciences
Chromium Radioisotopes
Dentistry
Female
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Humans
Immune Tolerance - immunology
Killer Cells, Natural - immunology
Male
Medical sciences
Middle Aged
Mouth Diseases - psychology
Mouth Neoplasms - psychology
Mouth Neoplasms - surgery
Pain - immunology
Pain - psychology
Quality of Life
Radiopharmaceuticals
Sex Factors
Smoking - psychology
Statistics as Topic
Stress, Psychological - immunology
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the upper aerodigestive tract
Surveys and Questionnaires
Tooth Diseases - psychology
Tumor Cells, Cultured
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective. Psychological stress has an influence on natural killer cell (NK) activity, which plays a central role in protection against microbial infection and cancer. Anxiety concerning cancer is a typical type of psychological stress observed in patients and is associated with various diseases. In this study, we examined whether anxiety about cancer reduces the NK activity or quality of life (QOL), or both, of outpatients. Patients and methods. NK activity was determined by means of a 4-hour 51chromium-release assay, and a QOL questionnaire by the World Health Organization called QOL-BRIEF was also used. One hundred forty-four patients were asked a variety of questions about anxiety with respect to cancer and pain on their first visit to the outpatient clinic of our Department of Oral Surgery. Results. The NK activity in patients with anxiety about cancer was significantly lower (P
ISSN:1079-2104
1528-395X
DOI:10.1067/moe.2001.115465