Plasma levels of coenzyme Q(10), vitamin E and lipids in uremic patients on conservative therapy and hemodialysis treatment: some possible biochemical and clinical implications

Coenzyme Q(10) (CoQ(10)), vitamin E, total cholesterol, HDL-cholesterol (HDLC) and triglycerides were measured in the plasma of 62 patients with kidney failure, 46 under hemodialysis treatment and 16 under conservative therapy, and 95 controls. The sum of LDL-cholesterol (LDL-C) and VLDL-cholesterol...

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Bibliographic Details
Published in:Clinica chimica acta 2000-02, Vol.292 (1-2), p.81-91
Main Authors: Lippa, S, Colacicco, L, Bondanini, F, Callà, C, Gozzo, M L, Ciccariello, M, Angelitti, A G
Format: Article
Language:English
Subjects:
Aged
Case-Control Studies
Cholesterol, LDL - blood
Cholesterol, VLDL - blood
Coenzymes
Creatinine - blood
Humans
Lipid Peroxidation
Lipids - blood
Middle Aged
Renal Dialysis
Ubiquinone - analogs & derivatives
Ubiquinone - blood
Uremia - blood
Uremia - therapy
Vitamin E - blood
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Summary:Coenzyme Q(10) (CoQ(10)), vitamin E, total cholesterol, HDL-cholesterol (HDLC) and triglycerides were measured in the plasma of 62 patients with kidney failure, 46 under hemodialysis treatment and 16 under conservative therapy, and 95 controls. The sum of LDL-cholesterol (LDL-C) and VLDL-cholesterol (VLDL-C) was also calculated for each patient. The ratio CoQ(10)/LDL-C+VLDL-C in both conservative therapy and hemodialysis populations was significantly lower (P
ISSN:0009-8981
DOI:10.1016/S0009-8981(99)00204-1