Predictors of death and reinfarction at 30 days after primary angioplasty : The GUSTO IIb and RAPPORT trials

Thirty-day death among recipients of fibrinolytic therapy for acute myocardial infarction (MI) is tightly correlated with easily obtainable key demographic and clinical parameters such as age, blood pressure, heart rate, and infarct location. Similar data for primary angioplasty are not available. D...

Full description

Saved in:
Bibliographic Details
Published in:The American heart journal 2000-03, Vol.139 (3), p.476-481, Article a102197
Main Authors: BRENER, S. J, ELLIS, S. G, SAPP, S. K, BETRIU, A, GRANGER, C. B, BURCHENAL, J. E. B, MOLITERNO, D. J, CALIFF, R. M, TOPOL, E. J
Format: Article
Language:English
Subjects:
Age Distribution
Aged
Aged, 80 and over
Angioplasty, Balloon, Coronary - adverse effects
Biological and medical sciences
Cardiology. Vascular system
Comorbidity
Coronary heart disease
Diabetes Mellitus - epidemiology
Female
Heart
Heart Rate
Humans
Hypertension - epidemiology
Incidence
Logistic Models
Male
Medical sciences
Middle Aged
Multivariate Analysis
Myocardial Infarction - epidemiology
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Odds Ratio
Prospective Studies
Randomized Controlled Trials as Topic
Risk Factors
Sex Distribution
Smoking - epidemiology
Survival Rate
Thrombolytic Therapy
Treatment Outcome
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Thirty-day death among recipients of fibrinolytic therapy for acute myocardial infarction (MI) is tightly correlated with easily obtainable key demographic and clinical parameters such as age, blood pressure, heart rate, and infarct location. Similar data for primary angioplasty are not available. Data from 2 large, contemporary, primary angioplasty trials were formally combined and analyzed with respect to death and death/repeat MI at 30 days through the use of multivariate logistic regression models. The 1048 patients had a median age of 62 years, and 26% were women. Thirty-eight percent had an anterior infarction. The patients underwent angioplasty at a median delay from symptom onset of 3.8 hours. Death was independently predicted by increasing age (adjusted odds ratio [OR] per decade 2.32, 95% confidence interval [CI] 1.60 to 3.42), whereas a history of smoking (OR 0.29, CI 0.13 to 0.64), Thrombolysis in Myocardial Infarction (TIMI) flow grade 3 after angioplasty (OR vs TIMI
ISSN:0002-8703
1097-6744
DOI:10.1067/mhj.2000.102197