Improved Resolution in Proton NMR Spectroscopy of Powdered Solids

We present a new solid-state nuclear magnetic resonance experiment that yields, under CRAMPS decoupling conditions, a significant reduction in proton line widths for powdered organic solids. This experiment which relies on a constant-time acquisition of the proton transverse magnetization, removes t...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Chemical Society 2001-06, Vol.123 (24), p.5747-5752
Main Authors: Lesage, Anne, Duma, Luminita, Sakellariou, Dimitris, Emsley, Lyndon
Format: Article
Language:English
Subjects:
Alanine - chemistry
Dipeptides - chemistry
Magnetics
Nuclear Magnetic Resonance, Biomolecular - instrumentation
Nuclear Magnetic Resonance, Biomolecular - methods
Powders - chemistry
Protons
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We present a new solid-state nuclear magnetic resonance experiment that yields, under CRAMPS decoupling conditions, a significant reduction in proton line widths for powdered organic solids. This experiment which relies on a constant-time acquisition of the proton transverse magnetization, removes the contribution of nonrefocusable broadening from the proton line widths. Although this new technique suffers from relatively low sensitivity, we demonstrate in this paper its feasibility on two model samples, l-alanine and the dipeptide Ala-Asp. In both cases a factor of between 2 and 3 in line width reduction is obtained for most of the proton resonances.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja0039740