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Early and delayed consolidation chemotherapy significantly improves the outcome of children with intermediate risk acute lymphoblastic leukemia. Final results of the prospective randomized PETHEMA ALL-89 TRIAL

Haematology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. jmribera@ns.hugtip.scs.es BACKGROUND AND OBJECTIVES: To evaluate the impact of early and delayed consolidation chemotherapy on the outcome of children with acute lymphoblastic leukemia (ALL) stratified according to...

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Published in:Haematologica (Roma) 2001-06, Vol.86 (6), p.586-595
Main Authors: Ortega, JJ, Ribera, JM, Oriol, A, Bastida, P, Gonzalez, ME, Calvo, C, Egurbide, I, Hernandez Rivas, JM, Rivas, C, Alcala, A, Besalduch, J, Macia, J, Gardella, S, Carnero, M, Lite, JM, Casanova, F, Martinez, M, Fontanillas, M, Feliu, E, San Miguel, JF, PETHEMA Group, Spanish Society of Hematology. Programa para el Estudio y Tratamiento de las Hemopatias Malignas
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container_end_page 595
container_issue 6
container_start_page 586
container_title Haematologica (Roma)
container_volume 86
creator Ortega, JJ
Ribera, JM
Oriol, A
Bastida, P
Gonzalez, ME
Calvo, C
Egurbide, I
Hernandez Rivas, JM
Rivas, C
Alcala, A
Besalduch, J
Macia, J
Gardella, S
Carnero, M
Lite, JM
Casanova, F
Martinez, M
Fontanillas, M
Feliu, E
San Miguel, JF
PETHEMA Group, Spanish Society of Hematology. Programa para el Estudio y Tratamiento de las Hemopatias Malignas
description Haematology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. jmribera@ns.hugtip.scs.es BACKGROUND AND OBJECTIVES: To evaluate the impact of early and delayed consolidation chemotherapy on the outcome of children with acute lymphoblastic leukemia (ALL) stratified according to risk groups. DESIGN AND METHODS: From 1989 to 1994, 195 children (
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identifier ISSN: 0390-6078
ispartof Haematologica (Roma), 2001-06, Vol.86 (6), p.586-595
issn 0390-6078
1592-8721
language eng
recordid cdi_proquest_miscellaneous_70929086
source Freely Accessible Science Journals
subjects Antineoplastic agents
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - standards
Biological and medical sciences
Chemotherapy
Child
Child, Preschool
Drug Administration Schedule
Female
Humans
Male
Medical sciences
Pharmacology. Drug treatments
Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy
Prospective Studies
Risk Factors
Time Factors
Treatment Outcome
title Early and delayed consolidation chemotherapy significantly improves the outcome of children with intermediate risk acute lymphoblastic leukemia. Final results of the prospective randomized PETHEMA ALL-89 TRIAL
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