effects of a unilateral ultrasound-guided renal biopsy on renal function in healthy sedated cats

Complications of renal biopsies are well documented except for the change in renal function after a biopsy. Eighteen healthy, adult cats were divided into two groups (n = 9 cats/group). For the measurement of global and split renal function, Group 1 used the renal uptake of 99mTc‐DTPA and Group 2 us...

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Bibliographic Details
Published in:Veterinary radiology & ultrasound 2000, Vol.41 (1), p.57-62
Main Authors: Drost, W.T, Henry, G.A, Meinkoth, J.H, Woods, J.P, Payton, M.E, Rodebush, C
Format: Article
Language:English
Subjects:
99mTc-DTPA
99mTc-MAG3
Anesthetics, Dissociative - administration & dosage
Animals
biopsy
Biopsy - adverse effects
Biopsy - veterinary
Cat
cats
Cats - anatomy & histology
complications
Conscious Sedation
Female
glomerular filtration rate
ketamine
Ketamine - administration & dosage
Kidney - diagnostic imaging
Kidney - pathology
Kidney - physiopathology
Kidney Cortex - diagnostic imaging
Kidney Cortex - pathology
kidneys
Liver - diagnostic imaging
Male
Radionuclide Imaging
Radiopharmaceuticals
Random Allocation
renal function
scintigraphy
technetium
Technetium Tc 99m Mertiatide
Technetium Tc 99m Pentetate
ultrasonography
Ultrasonography, Interventional - veterinary
ultrasound guided biopsy
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Summary:Complications of renal biopsies are well documented except for the change in renal function after a biopsy. Eighteen healthy, adult cats were divided into two groups (n = 9 cats/group). For the measurement of global and split renal function, Group 1 used the renal uptake of 99mTc‐DTPA and Group 2 used the renal uptake of 99mTc‐MAG3. Scintigraphic data were collected on days (‐4), (‐3), 0,1, 2, and 4 post renal biopsy. Using ultrasound guidance, biopsies were taken from the right renal cortex on d0, before acquiring scintigraphic images. P ‐ values less than 0.10 were considered significant due to the limited number of observations. The only statistically significant change (p = 0.08) in global renal function detected was by day following a unilateral renal biopsy. Cats imaged using 99mTc‐MAG3 had discernible liver activity. A unilateral, ultrasound guided renal biopsy has minimal effect on renal function in normal, healthy sedated cats.
ISSN:1058-8183
1740-8261
DOI:10.1111/j.1740-8261.2000.tb00428.x