Endoderm development: from patterning to organogenesis

Although the ectoderm and mesoderm have been the focus of intensive work in the recent era of studies on the molecular control of vertebrate development, the endoderm has received less attention. Because signaling must occur between germ layers in order to achieve a properly organized body, our unde...

Full description

Saved in:
Bibliographic Details
Published in:Trends in Genetics 2000-03, Vol.16 (3), p.124-130
Main Authors: Grapin-Botton, Anne, Melton, Douglas A
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cell Adhesion
Cell Differentiation
Cell differentiation, maturation, development, hematopoiesis
Cell Lineage
Cell physiology
Chick Embryo
Digestive System - embryology
Embryonic Induction
Endocrine Glands - embryology
endoderm
Endoderm - physiology
Endotherm patterning
Fundamental and applied biological sciences. Psychology
Gene Expression Regulation, Developmental
Genes, Homeobox
Gut
Intestine
Molecular and cellular biology
Morphogenesis
Organogenesis
Pancreas
Stomach
Vertebrate development
Vertebrates - embryology
Xenopus laevis - embryology
Zebrafish - embryology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although the ectoderm and mesoderm have been the focus of intensive work in the recent era of studies on the molecular control of vertebrate development, the endoderm has received less attention. Because signaling must occur between germ layers in order to achieve a properly organized body, our understanding of the coordinated development of all organs requires a more thorough consideration of the endoderm and its derivatives. This review focuses on present knowledge and perspectives concerning endoderm patterning and organogenesis. Some of the classical embryology of the endoderm is discussed and the progress and deficiencies in cellular and molecular studies are noted.
ISSN:0168-9525
DOI:10.1016/S0168-9525(99)01957-5