Antihyperglycemic activity of Teramnus labialis (Fabaceae)

In vivo bioassay-guided fractionation of the aqueous alcohol extract of the aerial parts of Teramnus labialis (Roxb.) Benth. (Fabaceae), using C57BL/Ks- db/db mice as a model for type 2 diabetes, yielded an active fraction containing a mixture of coumarins. The major coumarin present in the active f...

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Bibliographic Details
Published in:Phytomedicine (Stuttgart) 2000, Vol.6 (6), p.465-467
Main Authors: Fort, D.M., Rao, K., Jolad, S.D., Luo, J., Carlson, T.J., King, S.R.
Format: Article
Language:English
Subjects:
Animals
Antihyperglycemic activity
Fraxidin
Hypoglycemic Agents - pharmacology
Male
Mice
Mice, Inbred C57BL
Plant Extracts - pharmacology
Plants, Medicinal - chemistry
Rats
Teramnus labialis
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Summary:In vivo bioassay-guided fractionation of the aqueous alcohol extract of the aerial parts of Teramnus labialis (Roxb.) Benth. (Fabaceae), using C57BL/Ks- db/db mice as a model for type 2 diabetes, yielded an active fraction containing a mixture of coumarins. The major coumarin present in the active fraction was identified as fraxidin.
ISSN:0944-7113
1618-095X
DOI:10.1016/S0944-7113(00)80075-6